Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is
characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in …

At present, the etiology of idiopathic pulmonary fibrosis (IPF) remains elusive. Over the past
two decades, however, researchers have identified and described the underlying processes …

The aging of the human population has resulted in an unprecedented increase in the
incidence and prevalence of age-related diseases, including those of the lung. Idiopathic …

Idiopathic pulmonary fibrosis (IPF) is a chronic age-related lung disease with high mortality
that is characterized by abnormal scarring of the lung parenchyma. There has been a recent …

Mechanisms underlying the pathogenesis of pulmonary fibrosis remain incompletely
understood. Emerging evidence suggests changes in mitochondrial quality control are a …

The use of exogenous mitochondria to replenish damaged mitochondria has been proposed
as a strategy for the treatment of pulmonary fibrosis. However, the success of this strategy is …

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease of unknown
etiology with limited treatment options. It is characterized by repetitive injury to alveolar …

Pulmonary fibrosis is a progressive and intractable lung disease with fibrotic features that
affects alveoli elasticity, which leading to higher rates of hospitalization and mortality …

Background Impaired mitochondria homeostasis and function are established hallmarks of
aging and increasing evidence suggests a link with lung fibrosis. Mitochondria homeostasis …

Oxidative stress has been linked to various disease states as well as physiological aging.
The lungs are uniquely exposed to a highly oxidizing environment and have evolved several …