Enzymes in the synthesis of glycoconjugates

RM Schmaltz, SR Hanson, CH Wong - Chemical reviews, 2011 - ACS Publications
Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

Synthesis of glycosides by glycosynthases

MR Hayes, J Pietruszka - Molecules, 2017 - mdpi.com
The many advances in glycoscience have more and more brought to light the crucial role of
glycosides and glycoconjugates in biological processes. Their major influence on the …

Synthesis of complex carbohydrates and glycoconjugates: enzyme-based and programmable one-pot strategies

KM Koeller, CH Wong - Chemical Reviews, 2000 - ACS Publications
Identifying the functional roles of carbohydrates in biological systems has been an area of
intense study in recent years. Although carbohydrates were once viewed only as inert …

Glycosidases and glycosyl transferases in glycoside and oligosaccharide synthesis

DHG Crout, G Vic - Current opinion in chemical biology, 1998 - Elsevier
Remarkable advances in glycobiology in recent years have stimulated a resurgence of
interest in carbohydrate chemistry. The challenge of producing the complex glycosides and …

[图书][B] Modern methods in carbohydrate synthesis

SH Khan - 2020 - books.google.com
Modern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters
leading from classical methods through to today's newest state-of-the-art technology for …

Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies

KM Koeller, CH Wong - Glycobiology, 2000 - academic.oup.com
The ultimate goal in complex carbohydrate synthesis is to develop synthetic tools which are
simple and easily accessible to glycobiologists. This review will describe methods which …

Enzyme-catalyzed synthesis of carbohydrates

EJ Toone, ES Simon, MD Bednarski, GM Whitesides - Tetrahedron, 1989 - Elsevier
Carbohydrates are one of the most important classes of compounds in biology. ls In cells, for
example. carbohydrates function as structural components, to regulate viscosity, for energy …

Enzyme-catalyzed formation of glycosidic linkages

GM Watt, PAS Lowden, SL Flitsch - Current Opinion in Structural Biology, 1997 - Elsevier
Significant progress has recently been achieved in the use of glycosidases and
glycosyltransferases as synthetic tools. Glycosidases have been used to synthesize …

Teaching old enzymes new tricks: engineering and evolution of glycosidases and glycosyl transferases for improved glycoside synthesis

FA Shaikh, SG Withers - Biochemistry and Cell Biology, 2008 - cdnsciencepub.com
The therapeutic potential of glycosides has made them an attractive target for drug
development. The biological extraction and chemical synthesis of these molecules is often …

Chemical and enzymatic synthesis of glycopolymers

SL Flitsch - Current Opinion in Chemical Biology, 2000 - Elsevier
The development of efficient, fast, flexible and general synthetic routes to glycopolymers is
an ongoing challenge and much progress has been made in recent years. Chemical …