C-terminal determinants for RNA binding motif 7 protein stability and RNA recognition
AM Sobeh, CD Eichhorn - Biophysical chemistry, 2023 - Elsevier
The 7SK ribonucleoprotein (RNP) is a critical regulator of eukaryotic transcription. Recently,
RNA binding motif 7 (RBM7) containing an RNA recognition motif (RRM) was reported to …
RNA binding motif 7 (RBM7) containing an RNA recognition motif (RRM) was reported to …
Structural and dynamic studies of the human RNA binding protein RBM3 reveals the molecular basis of its oligomerization and RNA recognition
Human RNA‐binding motif 3 protein (RBM3) is a cold‐shock protein which functions in
various aspects of global protein synthesis, cell proliferation and apoptosis by interacting …
various aspects of global protein synthesis, cell proliferation and apoptosis by interacting …
Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7
E Uchikawa, KS Natchiar, X Han, F Proux… - Nucleic acids …, 2015 - academic.oup.com
The non-coding RNA 7SK is the scaffold for a small nuclear ribonucleoprotein (7SKsnRNP)
which regulates the function of the positive transcription elongation factor P-TEFb in the …
which regulates the function of the positive transcription elongation factor P-TEFb in the …
RNA recognition motifs: boring? Not quite
The RNA recognition motif (RRM) is one of the most abundant protein domains in
eukaryotes. While the structure of this domain is well characterized by the packing of two α …
eukaryotes. While the structure of this domain is well characterized by the packing of two α …
Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45
X Chen, Z Yang, W Wang, K Qian, M Liu… - Nucleic Acids …, 2021 - academic.oup.com
RBM45 is an RNA-binding protein involved in neural development, whose aggregation is
associated with neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) …
associated with neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) …
RRM–RNA recognition: NMR or crystallography… and new findings
GM Daubner, A Cléry, FHT Allain - Current opinion in structural biology, 2013 - Elsevier
To characterize protein–RNA recognition at the molecular level, structural biology has
turned out to be an indispensable approach. Detailed and direct insights into the mechanism …
turned out to be an indispensable approach. Detailed and direct insights into the mechanism …
Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein
Y Lin, KT Tan, J Liu, X Kong, Z Huang, XQ Xu - The International Journal of …, 2018 - Elsevier
RNA binding proteins serve as critical molecular switches in a multitude of post-
transcriptional regulatory processes. In the heart and muscles, the tissue specific RNA …
transcriptional regulatory processes. In the heart and muscles, the tissue specific RNA …
Structural characterization of RNA binding to RNA recognition motif (RRM) domains using data integration, 3D modeling and molecular dynamic simulation
H Dhondge - 2023 - theses.hal.science
This thesis was carried out in the frame of a larger European project (ITN RNAct) in which
computer science and biology approaches were combined to make progress towards the …
computer science and biology approaches were combined to make progress towards the …
Solution structure of the second RRM domain of RBM5 and its unusual binding characters for different RNA targets
The RNA binding motif protein 5 (RBM5), also known as LUCA15 or H37, containing two
RNA recognition motifs, is a component of the spliceosome A complex. Previously, it has …
RNA recognition motifs, is a component of the spliceosome A complex. Previously, it has …
The RNA recognition motif domains of RBM5 are required for RNA binding and cancer cell proliferation inhibition
L Zhang, Q Zhang, Y Yang, C Wu - Biochemical and biophysical research …, 2014 - Elsevier
RBM5 is a known putative tumor suppressor gene that has been shown to function in cell
growth inhibition by modulating apoptosis. RBM5 also plays a critical role in alternative …
growth inhibition by modulating apoptosis. RBM5 also plays a critical role in alternative …