Fish oil feeding attenuates neuroinflammatory gene expression without concomitant changes in brain eicosanoids and docosanoids in a mouse model of Alzheimer's …
Background Neuroinflammation is a recognized hallmark of Alzheimer's disease, along with
accumulation of amyloid-β plaques, neurofibrillary tangles and synaptic loss. n-3 …
accumulation of amyloid-β plaques, neurofibrillary tangles and synaptic loss. n-3 …
Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice
KE Hopperton, MO Trépanier, V Giuliano… - Journal of …, 2016 - Springer
Background Neuroinflammation is a proposed mechanism by which Alzheimer's disease
(AD) pathology potentiates neuronal death and cognitive decline. Consumption of omega-3 …
(AD) pathology potentiates neuronal death and cognitive decline. Consumption of omega-3 …
[HTML][HTML] Omega-3 polyunsaturated fatty acids and oxylipins in neuroinflammation and management of Alzheimer disease
JG Devassy, S Leng, M Gabbs, M Monirujjaman… - Advances in …, 2016 - Elsevier
Alzheimer disease (AD) is becoming one of the most prevalent neurodegenerative
conditions worldwide. Although the disease progression is becoming better understood …
conditions worldwide. Although the disease progression is becoming better understood …
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a …
Y Dong, M Xu, AV Kalueff, C Song - European journal of nutrition, 2018 - Springer
Abstract Purpose Interleukin (IL)-1β can activate glial cells to trigger neuroinflammation and
neurodegeneration. Lower omega (n)-3 polyunsaturated fatty acids (PUFAs) and lower n-3/n …
neurodegeneration. Lower omega (n)-3 polyunsaturated fatty acids (PUFAs) and lower n-3/n …
The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus
Background Neuroinflammation is thought to contribute to psychiatric and neurological
disorders such as major depression and Alzheimer's disease (AD). N-6 polyunsaturated fatty …
disorders such as major depression and Alzheimer's disease (AD). N-6 polyunsaturated fatty …
Role of docosahexaenoic acid in the modulation of glial cells in Alzheimer's disease
D Heras-Sandoval, J Pedraza-Chaverri… - Journal of …, 2016 - Springer
Docosahexaenoic acid (DHA) is an omega-3 (ω-3) long-chain polyunsaturated fatty acid
(LCPUFA) relevant for brain function. It has largely been explored as a potential candidate to …
(LCPUFA) relevant for brain function. It has largely been explored as a potential candidate to …
Experimental models and mechanisms underlying the protective effects of n-3 polyunsaturated fatty acids in Alzheimer's disease
C Boudrault, RP Bazinet, DWL Ma - The Journal of nutritional biochemistry, 2009 - Elsevier
Dementia such as Alzheimer's disease (AD) is a growing health problem in aging
populations in many countries around the world. Currently, there is no cure for AD; …
populations in many countries around the world. Currently, there is no cure for AD; …
The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production
JR Lowry, N Marshall, TJ Wenzel, TE Murray… - Molecular and Cellular …, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder without a known cure or effective
treatment. Research has identified several modifiable risk factors and suggested …
treatment. Research has identified several modifiable risk factors and suggested …
Endogenous docosahexaenoic acid (dha) prevents aβ1–42 oligomer-induced neuronal injury
The intake of the polyunsaturated fatty acid docosahexaenoic acid (DHA) or n-3 fatty acid
has been associated with reduced risk of Alzheimer's disease (AD) in epidemiological …
has been associated with reduced risk of Alzheimer's disease (AD) in epidemiological …
Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-κB pathway in presenilin 1/2 …
J Gao, L Wang, C Zhao, Y Wu, Z Lu, Y Gu… - Journal of leukocyte …, 2021 - academic.oup.com
Chronic neuroinflammation has been shown to exert adverse influences on the pathology of
Alzheimer's disease (AD), associated with the release of abundant proinflammatory …
Alzheimer's disease (AD), associated with the release of abundant proinflammatory …