Background A nonsputum blood test capable of predicting progression of healthy individuals
to active tuberculosis (TB) before clinical symptoms manifest would allow targeted treatment …

Summary Background Biomarkers correlating with Mycobacterium tuberculosis infection
activity/burden in asymptomatic individuals are urgently needed to identify and treat those at …

Biomarkers for TB treatment response and outcome are needed. This study characterize
changes in immune profiles during TB treatment, define biosignatures associated with …

New approaches to control tuberculosis (TB) worldwide are needed. In particular, new tools
for diagnosis and new biomarkers are required to evaluate both pathogen and host key …

Tuberculosis (TB) is a leading cause of morbidity and mortality from a single infectious
agent, despite being preventable and curable. Early and accurate diagnosis of active TB is …

New non-sputum biomarker tests for active tuberculosis (TB) diagnostics are of the highest
priority for global TB control. We performed in-depth proteomic analysis using the 4,000-plex …

Tuberculosis (TB) is a deadly infectious disease that affects millions of people globally. TB
proteomics signature discovery has been a rapidly growing area of research that aims to …

Accurate and affordable point-of-care diagnostics for tuberculosis (TB) are needed. Host
serum protein signatures have been derived for use in primary care settings, however …

Millions of cases of tuberculosis (TB) go undiagnosed each year. Better diagnostic tools are
urgently needed. Biomarker-based or multiple marker biosignature-based tests, ideally …

Accurate and rapid diagnosis of active tuberculosis (TB) disease is still hampered by
inadequate tools. Although current assays relying on single-marker readouts mostly display …