Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

Q Chen, P Shou, C Zheng, M Jiang, G Cao… - Cell Death & …, 2016 - nature.com
Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …

Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: cross talk with the osteoblastogenic program

S Muruganandan, AA Roman, CJ Sinal - Cellular and molecular life …, 2009 - Springer
Bone marrow mesenchymal stem cells (MSCs) are multipotent cells, which among other cell
lineages, give rise to adipocytes and osteoblasts. Within the bone marrow, the differentiation …

Mechanisms underlying the osteo‐and adipo‐differentiation of human mesenchymal stem cells

Y Zhang, D Khan, J Delling… - The Scientific World …, 2012 - Wiley Online Library
Human mesenchymal stem cells (hMSCs) are considered a promising cell source for
regenerative medicine, because they have the potential to differentiate into a variety of …

In osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis

AM Pino, CJ Rosen, JP Rodríguez - Biological research, 2012 - SciELO Chile
The formation, maintenance, and repair of bone tissue involve close interlinks between two
stem cell types housed in the bone marrow: the hematologic stem cell originating …

[HTML][HTML] Markers are shared between adipogenic and osteogenic differentiated mesenchymal stem cells

M Köllmer, JS Buhrman, Y Zhang… - … biology and tissue …, 2013 - ncbi.nlm.nih.gov
The stem cell differentiation paradigm is based on the progression of cells through
generations of daughter cells that eventually become restricted and committed to one …

Bone marrow adipose tissue and skeletal health

S Muruganandan, R Govindarajan, CJ Sinal - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review To summarize and discuss recent progress and novel signaling
mechanisms relevant to bone marrow adipocyte formation and its physiological …

Identification of common pathways mediating differentiation of bone marrow-and adipose tissue-derived human mesenchymal stem cells into three mesenchymal …

TM Liu, M Martina, DW Hutmacher, JHP Hui… - Stem …, 2007 - academic.oup.com
Mesenchymal stem cells derived from human bone marrow (hBMSCs) and human adipose
tissue (hAMSCs) represent a useful source of progenitor cells for cell therapy and tissue …

Demonstration of the presence of independent pre-osteoblastic and pre-adipocytic cell populations in bone marrow-derived mesenchymal stem cells

S Post, BM Abdallah, JF Bentzon, M Kassem - Bone, 2008 - Elsevier
Mesenchymal stem cells (MSC) are defined as plastic-adherent, clonal cells that are
common progenitors for osteoblasts and adipocytes. An inverse relationship between bone …

The bone marrow-derived stromal cells: commitment and regulation of adipogenesis

M Tencerova, M Kassem - Frontiers in endocrinology, 2016 - frontiersin.org
Bone marrow (BM) microenvironment represents an important compartment of bone that
regulates bone homeostasis and the balance between bone formation and bone resorption …

Defining osteoblast and adipocyte lineages in the bone marrow

JL Pierce, DL Begun, JJ Westendorf… - Bone, 2019 - Elsevier
Bone is a complex endocrine organ that facilitates structural support, protection to vital
organs, sites for hematopoiesis, and calcium homeostasis. The bone marrow …