Changes correlating with increasing obesity include insulin resistance, hyperlipidaemia,
hyperinsulinaemia, highly processed food and environmental toxins including plastics and …

Objective High levels of reactive oxygen species (ROS) are intricately linked to obesity and
associated pathologies, notably insulin resistance and type 2 diabetes. However, ROS are …

In the last few years, several studies have shown a strong association among obesity,
altered redox state and inflammation; these studies have also shown that such alterations …

This special issue presents a range of papers exploring the inter-relationship between
metabolism and inflammation in dietrelated metabolic disease, as well as focusing on …

Studies report on the association between obesity and oxidative stress, with and without
additional diseases. Macrophages in adipocytes, and hypoxia in adipose tissue have been …

An increase in reactive oxygen species (ROS) and a decrease in endogenous antioxidant
defense mechanisms are observed in both aging and diabetes. The mechanisms driving an …

Oxygen metabolism produces a series of oxygen-free radicals (reactive oxygen species or
ROS), which are highly unstable and can lead to functional impairment of or damage to …

The rate of substrate oxidation varies considerably during the day, being dictated by the
body's need to regenerate the adenosine triphosphate (ATP) used in carrying out its …

There are different types of nutritionally mediated oxidative stress sources that trigger
inflammation. Much information indicates that high intakes of macronutrients can promote …

Metabolic plasticity is the ability of a biological system to adapt its metabolic phenotype to
different environmental stressors. We used a whole-body and tissue-specific phenotypic …