Background There is a need for novel analgesics with favorable risk to benefit profiles.
Oxytocin has recently gained attention for its potential analgesic properties. Aim The aim of …

Objectives: A review of the literature was conducted to assess the association between
oxytocin (OT) and pain. Methods: PsychInfo, PubMed, and Medline (EBSCO) research …

In an acute environment pain has potential protective benefits. However when pain
becomes chronic this protective effect is lost and the pain becomes an encumbrance …

Pain is a ubiquitously unpleasant feeling among humans as well as many animal species
often caused by actual and potential tissue damage. However, it is absolutely crucial for our …

Introduction Oxytocin (OXT) is a peptide hormone produced in the hypothalamus that plays a
neuromodulatory role in emotion, stress, and anxiety. Due to its multidimensional role, OXT …

The treatment of chronic pain arising from deep tissues is currently inadequate and there is
need for new pharmacological agents to provide analgesia. The endogenous paracrine …

Oxytocin, a neuropeptide crucial for social bonding and reproduction, has captivated
scientific interest due to its diverse mechanisms, physiological effects, and therapeutic …

Background There is increasing evidence for oxytocin as a neurotransmitter in spinal
nociceptive processes. Hypothalamic oxytocinergic neurons project to the spinal dorsal …

Introduction This protocol presents the rationale and design for a trial evaluating the efficacy
of intranasal oxytocin in improving pain and function among women with chronic pelvic …

Methods| In January to September 2012, we recruited 80 healthy male volunteers at the
University of Hamburg, Germany. Based on previous data, we expected this sample size to …