Enhanced anti-glioblastoma efficacy by PTX-loaded PEGylated poly (ɛ-caprolactone) nanoparticles: in vitro and in vivo evaluation

H Xin, L Chen, J Gu, X Ren, J Luo, Y Chen… - International journal of …, 2010 - Elsevier
The aim of this work was to investigate the anti-tumor effect of paclitaxel (PTX)-loaded
methoxy poly (ethylene glycol)-poly (ɛ-caprolactone) nanoparticles (MPEG-NP/PTX) against …

PEGylated poly (trimethylene carbonate) nanoparticles loaded with paclitaxel for the treatment of advanced glioma: in vitro and in vivo evaluation

X Jiang, H Xin, X Sha, J Gu, Y Jiang, K Law… - International journal of …, 2011 - Elsevier
The aim of this study was to investigate the antitumor effect of paclitaxel (PTX)-loaded poly
(ethylene glycol)–poly (trimethylene carbonate)(MPEG–PTMC) nanoparticles (NP) against …

Effect of Paclitaxel/etoposide co-loaded polymeric nanoparticles on tumor size and survival rate in a rat model of glioblastoma

H Maleki, MRH Najafabadi, TJ Webster… - International journal of …, 2021 - Elsevier
The aim of this work is to co-load paclitaxel (PTX) and etoposide (ETP) in methoxy poly
(ethylene glycol)-poly (lactic-co-glycolic acid) nanoparticles (mPEG-PLGA NPs) to overcome …

Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation

F Madani, SS Esnaashari, MC Bergonzi, TJ Webster… - Life sciences, 2020 - Elsevier
Aim The aim of this study was to improve the therapeutic index of chemotherapeutic drugs
on glioblastoma cells through an improved co-drug delivery system. Materials and methods …

Paclitaxel-loaded poly (N-vinylpyrrolidone)-b-poly (ε-caprolactone) nanoparticles: preparation and antitumor activity in vivo

Z Zhu, Y Li, X Li, R Li, Z Jia, B Liu, W Guo, W Wu… - Journal of Controlled …, 2010 - Elsevier
Paclitaxel (PTX)-loaded poly (N-vinylpyrrolidone)-b-poly (ε-caprolactone)(PVP-b-PCL)
nanoparticles with high drug payload were successfully prepared by a modified nano …

Formulation and evaluation of paclitaxel-loaded polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer

T Araki, Y Kono, K Ogawara, T Watanabe… - Biological and …, 2012 - jstage.jst.go.jp
To develop potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated
PTX into polymeric nanoparticles composed of polyethylene glycol (PEG) and polylactic acid …

Characterization, pharmacokinetics and disposition of novel nanoscale preparations of paclitaxel

C Wang, YJ Wang, YJ Wang, M Fan, F Luo… - International journal of …, 2011 - Elsevier
Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …

[HTML][HTML] Docetaxel loaded PEG-PLGA nanoparticles: optimized drug loading, in-vitro cytotoxicity and in-vivo antitumor effect

MN Koopaei, MR Khoshayand… - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
In this study a 3-factor, 3-level Box-Behnken design was used to prepare optimized
docetaxel (DTX) loaded pegylated poly lactide-co-glycolide (PEG-PLGA) Nanoparticles …

Free paclitaxel loaded PEGylated-paclitaxel nanoparticles: preparation and comparison with other paclitaxel systems in vitro and in vivo

J Lu, X Chuan, H Zhang, W Dai, X Wang… - International journal of …, 2014 - Elsevier
Abstract Previously, PEGylated paclitaxel (PEG-PTX) was found not favorable as a polymer
prodrug because of its poor antitumor efficiency. But surprisingly, it was found in our study …

Paclitaxel-loaded TPGS-b-PCL nanoparticles: in vitro cytotoxicity and cellular uptake in MCF-7 and MDA-MB-231 cells versus mPEG-b-PCL nanoparticles and …

E Bernabeu, L Gonzalez, MJ Legaspi… - … of nanoscience and …, 2016 - ingentaconnect.com
Nanomedicines have become an attractive platform for the development of novel drug
delivery systems in cancer chemotherapy. Polymeric nanoparticles (NPs) represent one of …