Functional improvement of human cardiotrophin 1 produced in tobacco chloroplasts by co-expression with plastid thioredoxin m
M Ancín Rípodas, R Sanz Barrio… - Plants, 2020, 9 …, 2020 - academica-e.unavarra.es
Human cardiotrophin 1 (CT1), a cytokine with excellent therapeutic potential, was previously
expressed in tobacco chloroplasts. However, the growth conditions required to reach the …
expressed in tobacco chloroplasts. However, the growth conditions required to reach the …
Functional improvement of human cardiotrophin 1 produced in tobacco chloroplasts by co-expression with plastid thioredoxin m
M Ancín, R Sanz-Barrio, E Santamaría… - Plants, 2020 - mdpi.com
Human cardiotrophin 1 (CT1), a cytokine with excellent therapeutic potential, was previously
expressed in tobacco chloroplasts. However, the growth conditions required to reach the …
expressed in tobacco chloroplasts. However, the growth conditions required to reach the …
High‐density seedling expression system for the production of bioactive human cardiotrophin‐1, a potential therapeutic cytokine, in transgenic tobacco chloroplasts
I Farran, F Río‐Manterola, M Íñiguez… - Plant biotechnology …, 2008 - Wiley Online Library
Summary Histidine‐tagged human cardiotrophin‐1 (hCT‐1), a recently discovered cytokine
with excellent therapeutic potential, was expressed in tobacco chloroplasts under the …
with excellent therapeutic potential, was expressed in tobacco chloroplasts under the …
Comprehensive Expression Analyses of Plastidial Thioredoxins of Arabidopsis thaliana Indicate a Main Role of Thioredoxin m2 in Roots
M Sahrawy, J Fernández-Trijueque, P Vargas… - Antioxidants, 2022 - mdpi.com
Thioredoxins (TRXs) f and m are redox proteins that regulate key chloroplast processes. The
existence of several isoforms of TRXs f and m indicates that these redox players have …
existence of several isoforms of TRXs f and m indicates that these redox players have …
Overexpression of plastidial thioredoxins f and m differentially alters photosynthetic activity and response to oxidative stress in tobacco plants
P Rey, R Sanz-Barrio, G Innocenti, B Ksas… - Frontiers in Plant …, 2013 - frontiersin.org
Plants display a remarkable diversity of thioredoxins (Trxs), reductases controlling the thiol
redox status of proteins. The physiological function of many of them remains elusive …
redox status of proteins. The physiological function of many of them remains elusive …
Production of biologically active human thioredoxin 1 protein in lettuce chloroplasts
S Lim, H Ashida, R Watanabe, K Inai, YS Kim… - Plant molecular …, 2011 - Springer
The production of human therapeutic proteins in plants provides opportunities for low-cost
production, and minimizes the risk of contamination from potential human pathogens …
production, and minimizes the risk of contamination from potential human pathogens …
Overexpression of thioredoxin m in chloroplasts alters carbon and nitrogen partitioning in tobacco
M Ancín, L Larraya, I Florez-Sarasa… - Journal of …, 2021 - academic.oup.com
In plants, there is a complex interaction between carbon (C) and nitrogen (N) metabolism,
and its coordination is fundamental for plant growth and development. Here, we studied the …
and its coordination is fundamental for plant growth and development. Here, we studied the …
Overexpression of thioredoxin m in tobacco chloroplasts inhibits the protein kinase STN7 and alters photosynthetic performance
M Ancín, A Fernández-San Millán… - Journal of …, 2019 - academic.oup.com
The activity of the protein kinase STN7, involved in phosphorylation of the light-harvesting
complex II (LHCII) proteins, has been reported as being co-operatively regulated by the …
complex II (LHCII) proteins, has been reported as being co-operatively regulated by the …
Functional division of f-type and m-type thioredoxins to regulate the Calvin cycle and cyclic electron transport around photosystem I
Redox regulation of chloroplast proteins is necessary to adjust photosynthetic performance
with changes in light. The thioredoxin (Trx) system plays a central role in this process …
with changes in light. The thioredoxin (Trx) system plays a central role in this process …
Thioredoxins in chloroplasts
SD Lemaire, L Michelet, M Zaffagnini, V Massot… - Current genetics, 2007 - Springer
Thioredoxins (TRXs) are small disulfide oxidoreductases of ca. 12 kDa found in all free living
organisms. In plants, two chloroplastic TRXs, named TRX f and TRX m, were originally …
organisms. In plants, two chloroplastic TRXs, named TRX f and TRX m, were originally …
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