A direct relationship between serum uric acid levels and hypertension, cardiovascular, renal
and metabolic diseases has been reported in many basic and epidemiological studies …

The association between serum uric acid levels and high blood pressure in humans is well
established. For example, a cross-sectional study determined that each 1mg/dL increase in …

The association between increased serum urate and hypertension has been a subject of
intense controversy. Extracellular uric acid drives uric acid deposition in gout, kidney stones …

Increased levels of uric acid are associated with cardiovascular disease and the metabolic
syndrome. They may predict clinical outcomes and also the onset of hypertension, though it …

Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …

A number of epidemiological studies have reported an association between serum uric acid
levels and a wide variety of high-risk conditions including hypertension, insulin resistance …

Over the last decade, the biologic interference of uric acid with the cardiovascular (CV)
system and the kidney has been intensively investigated, and several experimental studies …

Uric acid is a major product of purine metabolism in humans. Epidemiologic and
experimental evidence suggests that serum uric acid is an independent risk factor for …

Substantial evidence suggests that chronic hyperuricemia is an independent risk factor for
hypertension, metabolic syndrome, chronic kidney disease (CKD) and cardiovascular …

Hyperuricemia is associated with hypertension, vascular disease, renal disease, and
cardiovascular events. In this report, we review the epidemiologic evidence and potential …