Purpose. To validate microarray data on cytokeratin 13 (KRT13) and interleukin‐1 receptor
antagonist (IL1RN) expression in urothelial carcinoma of the urinary bladder (UCB) and to …

Background Cytokines are known to be a key a factor in numerous malignancies and to
exert an important regulatory role in the tumor microenvironment. Interest has grown in …

Background Urothelial carcinoma (UC) is one of most common genitourinary malignancy
and the spectrum of disease ranges from in situ lesions to muscle-invasive cancers. The non …

Background: Many researchers have tried to identify bladder cancer biomarkers to reduce
the need for cystoscopy. The aim of this study was to identify and measure appropriate …

Several evidences have been published linking polymorphism in genes involved in chronic
or recurrent inflammation with increased tumor risk and progression. Nevertheless the …

Previous data indicate a role of IL-1 and IL-1RA imbalance in bladder carcinoma (BC); the
inhibition of IL-1 signaling might be considered a treatment option. Objective: To assess …

Bladder cancer is universally acknowledged as a significant public health issue. Abundant
evidence shows that cigarette smoke (CS) is the primary risk factor for bladder cancer …

We used gene expression profiling to identify inflammatory cytokines that correlate with
bladder cancer development. Gene expression profiles of the tissue samples were …

Purpose We investigated the relationship between the distribution of the IL-1RN, TNF-β and
IL-4 polymorphism and the clinical features of bladder cancer. Materials and methods A total …

Smoking is considered an important risk factor for bladder cancer (BC), yet molecular
characterization of BC in nonsmokers has not been extensively studied. Here, we compare …