The effects of oxytocin on appetite regulation, food intake and metabolism in humans

L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

The effects of oxytocin on eating behaviour and metabolism in humans

EA Lawson - Nature Reviews Endocrinology, 2017 - nature.com
Oxytocin, a hypothalamic hormone that is secreted directly into the brain and enters the
peripheral circulation through the posterior pituitary gland, regulates a range of physiologic …

Oxytocin in metabolic homeostasis: implications for obesity and diabetes management

C Ding, MKS Leow, F Magkos - Obesity Reviews, 2019 - Wiley Online Library
Oxytocin was once understood solely as a neuropeptide with a central role in social
bonding, reproduction, parturition, lactation and appetite regulation. Recent evidence …

Role of oxytocin in energy metabolism

VE Chaves, CQ Tilelli, NA Brito, MN Brito - Peptides, 2013 - Elsevier
The basic mechanisms that lead obesity are not fully understood; however, several peptides
undoubtedly play a role in regulating body weight. Obesity, a highly complex metabolic …

Coming full circle: contributions of central and peripheral oxytocin actions to energy balance

JM Ho, JE Blevins - Endocrinology, 2013 - academic.oup.com
The neuropeptide oxytocin has emerged as an important anorexigen in the regulation of
energy balance. Its effects on food intake have largely been attributed to limiting meal size …

Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats

N Deblon, C Veyrat-Durebex, L Bourgoin, A Caillon… - PloS one, 2011 - journals.plos.org
Apart from its role during labor and lactation, oxytocin is involved in several other functions.
Interestingly, oxytocin-and oxytocin receptor-deficient mice develop late-onset obesity with …

Metabolic effects of oxytocin

SE McCormack, JE Blevins, EA Lawson - Endocrine reviews, 2020 - academic.oup.com
There is growing evidence that oxytocin (OXT), a hypothalamic hormone well recognized for
its effects in inducing parturition and lactation, has important metabolic effects in both sexes …

Current findings on the role of oxytocin in the regulation of food intake

MS Spetter, M Hallschmid - Physiology & behavior, 2017 - Elsevier
In the face of the alarming prevalence of obesity and its associated metabolic impairments, it
is of high basic and clinical interest to reach a complete understanding of the central …

Oxytocin's inhibitory effect on food intake is stronger in obese than normal-weight men

M Thienel, A Fritsche, M Heinrichs, A Peter… - International journal of …, 2016 - nature.com
Results: Oxytocin markedly reduced hunger-driven food intake in the fasted state in obese
but not in normal-weight men, and led to a reduction in snack consumption in both groups …

Oxytocin and food intake control: Neural, behavioral, and signaling mechanisms

CM Liu, MO Spaulding, JJ Rea, EE Noble… - International Journal of …, 2021 - mdpi.com
The neuropeptide oxytocin is produced in the paraventricular hypothalamic nucleus and the
supraoptic nucleus of the hypothalamus. In addition to its extensively studied influence on …