The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a
subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates a wide …

The c-Jun-NH 2-terminal kinase (JNK) signaling pathway plays a critical role in regulating
cell fate, being implicated in a multitude of diseases ranging from cancer to neurological and …

JNKs (c-Jun N-terminal kinases) belong to mitogen-activated protein kinases' family and
become activated by several growth factors, stress, radiation, and other extracellular signals …

The JNKs are master protein kinases that regulate many physiological processes, including
inflammatory responses, morphogenesis, cell proliferation, differentiation, survival and …

The c-Jun NH2-terminal kinases (JNKs) are an evolutionarily conserved sub-group of
mitogen-activated protein (MAP) kinases. Recent studies have improved our understanding …

The c-Jun N-terminal kinase (JNK) signalling pathway is a conserved response to a wide
range of internal and external cellular stress signals. Beside the stress response, the JNK …

The c-Jun NH2-terminal kinases (JNKs) phosphorylate and activate members of the
activator protein-1 (AP-1) transcription factor family and other cellular factors implicated in …

Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family
members function in a cell context-specific and cell type-specific manner to integrate signals …

In addition to marshalling immune and inflammatory responses, transcription factors of the
NF-κB family control cell survival. This control is crucial to a wide range of biological …

In inflamed tissue, normal signal transduction pathways are altered by extracellular signals.
For example, the JNK pathway is activated in psoriatic skin, which makes it an attractive …