Cirrhosis represents the end‐stage of any persistent chronically active liver disease. It is
characterized by the complete replacement of normal liver tissue by fibrosis, regenerative …

Objective: Cirrhosis is the common end stage of any given chronic liver disease, developing
after persistent destruction and regeneration of parenchymal liver cells. The associated …

Quantitative data defining the relationship between the hepatic microcirculation and the
development of liver pathological changes could provide a basis for a better understanding …

This intravital fluorescence microscopy (IVFM) study validates cirrhotic mice models and
describes the different intrahepatic alterations and the role of angiogenesis in the liver …

Abstract Purpose of Review Current research into the pathogenesis of cirrhosis is largely
dominated by investigations of hepatocellular injury and fibrogenesis, mostly in short-term …

Cirrhosis describes the development of excess fibrous tissue around regenerative nodules
in response to chronic liver injury and usually leads to irreversible organ damage and end …

Background/Aims: In this study, a detailed morphometrical analysis of the hepatic
microvasculature in the different zones of hepatic parenchyma was performed in normal and …

Although absolute organ shortage highlights the needs of alternative organ sources for
regenerative medicine, the generation of a three-dimensional (3D) and complex vital organ …

The intricate (micro) vascular architecture of the liver has not yet been fully unravelled.
Although current models are often idealized simplifications of the complex anatomical …

Although a full understanding of the hepatic circulation is one of the keys to successfully
perform liver surgery and to elucidate liver pathology, relatively little is known about the …