Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine

R Subbiah, RE Guldberg - Advanced healthcare materials, 2019 - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …

Engineering growth factors for regenerative medicine applications

AC Mitchell, PS Briquez, JA Hubbell, JR Cochran - Acta biomaterialia, 2016 - Elsevier
Growth factors are important morphogenetic proteins that instruct cell behavior and guide
tissue repair and renewal. Although their therapeutic potential holds great promise in …

Controlled growth factor delivery for tissue engineering

P Tayalia, DJ Mooney - Advanced materials, 2009 - Wiley Online Library
Growth factors play a crucial role in information transfer between cells and their
microenvironment in tissue engineering and regeneration. They initiate their action by …

Growth factor delivery: Defining the next generation platforms for tissue engineering

LMC Aguilar, SM Silva, SE Moulton - Journal of controlled Release, 2019 - Elsevier
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

K Lee, EA Silva, DJ Mooney - Journal of the Royal …, 2011 - royalsocietypublishing.org
The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

Stimuli‐responsive delivery of growth factors for tissue engineering

M Qu, X Jiang, X Zhou, C Wang, Q Wu… - Advanced …, 2020 - Wiley Online Library
Growth factors (GFs) play a crucial role in directing stem cell behavior and transmitting
information between different cell populations for tissue regeneration. However, their utility …

Biomaterials for sequestration of growth factors and modulation of cell behavior

SPB Teixeira, RMA Domingues… - Advanced Functional …, 2020 - Wiley Online Library
Growth factors (GFs) are proteins secreted by cells that regulate a variety of biological
processes. Although they have long been proposed as potent therapeutic agents, their …

Design of growth factor sequestering biomaterials

DG Belair, NN Le, WL Murphy - Chemical Communications, 2014 - pubs.rsc.org
Growth factors (GFs) are major regulatory proteins that can govern cell fate, migration, and
organization. Numerous aspects of the cell milieu can modulate cell responses to GFs, and …

Toward delivery of multiple growth factors in tissue engineering

FM Chen, M Zhang, ZF Wu - Biomaterials, 2010 - Elsevier
Inspired by physiological events that accompany the “wound healing cascade”, the concept
of developing a tissue either in vitro or in vivo has led to the integration of a wide variety of …

Growth factor-delivery systems for tissue engineering: a materials perspective

R Vasita, DS Katti - Expert review of medical devices, 2006 - Taylor & Francis
The transplantation of organs, their surgical reconstruction or implantation of synthetic
devices that can perform the function of organs, are the currently available methods for …