Metabolism and colorectal cancer

JC Sedlak, ÖH Yilmaz, J Roper - Annual Review of Pathology …, 2023 - annualreviews.org
Reprogrammed metabolism is a hallmark of colorectal cancer (CRC). CRC cells are geared
toward rapid proliferation, requiring nutrients and the removal of cellular waste in nutrient …

[HTML][HTML] Colorectal cancer and metabolism

RE Brown, SP Short, CS Williams - Current colorectal cancer reports, 2018 - Springer
Abstract Purpose of Review Metabolic reprogramming is essential for the rapid proliferation
of cancer cells and is thus recognized as a hallmark of cancer. In this review, we will discuss …

[HTML][HTML] Metabolic pathways regulating colorectal cancer initiation and progression

S La Vecchia, C Sebastián - Seminars in cell & developmental biology, 2020 - Elsevier
Colorectal cancer (CRC) is one of the most common types of cancer worldwide. Despite
recent advances in the molecular genetics of CRC, poor treatment outcomes highlight the …

Colorectal cancer: Metabolic interactions reshape the tumor microenvironment

J Chen, H Zhu, Y Yin, S Jia, X Luo - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Colorectal cancer (CRC) is one of the most common cancers worldwide, which ranks third in
terms of incidence and the second leading cause of cancer-related mortality. Metabolic …

Metabolic reprogramming of colorectal cancer cells and the microenvironment: implication for therapy

M Nenkov, Y Ma, N Gaßler, Y Chen - International journal of molecular …, 2021 - mdpi.com
Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

Interplay between diet, gut microbiota, epigenetic events, and colorectal cancer

SJ Bultman - Molecular nutrition & food research, 2017 - Wiley Online Library
Despite the success of colonoscopy screening, colorectal cancer (CRC) remains one of the
most common and deadly cancers, and CRC incidence is rising in some countries where …

Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment

M Hanus, D Parada-Venegas, G Landskron… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Gut microbiota-derived metabolites in colorectal cancer: the bad and the challenges

W Zhang, Y An, X Qin, X Wu, X Wang, H Hou… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence from studies in humans and animal models has elucidated that gut
microbiota, acting as a complex ecosystem, contributes critically to colorectal cancer (CRC) …

Diet, the gut microbiome, and epigenetics

MAJ Hullar, BC Fu - The Cancer Journal, 2014 - journals.lww.com
Increasingly, the gut microbiome is implicated in the etiology of cancer, not only as an
infectious agent but also by altering exposure to dietary compounds that influence disease …

The gut microbiota in conventional and serrated precursors of colorectal cancer

BA Peters, C Dominianni, JA Shapiro, TR Church, J Wu… - Microbiome, 2016 - Springer
Background Colorectal cancer is a heterogeneous disease arising from at least two
precursors—the conventional adenoma (CA) and the serrated polyp. We and others have …