Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency (CCSVI) in people with multiple sclerosis

VA Jagannath, E Pucci, GV Asokan… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Multiple sclerosis (MS) is a leading cause of neurological disability in young
adults. The most widely accepted hypothesis regarding its pathogenesis is that it is an …

Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis patients

EJ van Zuuren, Z Fedorowicz, E Pucci… - Cochrane Database …, 2012 - cochranelibrary.com
Background Multiple sclerosis (MS) is a leading cause of neurological disability in young
adults. The most widely accepted hypothesis regarding its pathogenesis is that it is an …

Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency in people with multiple sclerosis: a summary of a Cochrane …

EJ van Zuuren, Z Fedorowicz, E Pucci… - Journal of Neurology …, 2014 - jnnp.bmj.com
Background It has been recently hypothesised that chronic cerebrospinal venous
insufficiency (CCSVI) may be an important factor in the pathogenesis of multiple sclerosis …

Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple …

P Zamboni, A Bertolotto, P Boldrini, P Cenni… - Trials, 2012 - Springer
Background Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system with a disabling progressive course. Chronic cerebrospinal venous …

Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: a randomized clinical trial

P Zamboni, L Tesio, S Galimberti, L Massacesi… - JAMA …, 2018 - jamanetwork.com
Importance Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
restricted venous outflow from the brain and spinal cord. Whether this condition is …

An overview of randomized controlled trials on endovascular treatment for chronic cerebrospinal venous insufficiency in multiple sclerosis patients

M Simka - Phlebologie, 2021 - thieme-connect.com
About ten years ago it was hoped that venous angioplasty for abnormal veins, primarily the
internal jugular veins, will be a much awaited treatment for multiple sclerosis. Yet, a majority …

Percutaneous transluminal angioplasty for chronic cerebrospinal venous insufficiency in multiple sclerosis: dichotomy between subjective and objective outcome …

S Zagaglia, S Balestrini, E Perticaroli, MC Danni… - Neurological …, 2013 - Springer
Some multiple sclerosis (MS) patients reported an improvement after percutaneous
transluminal angioplasty (PTA) for chronic cerebrospinal venous insufficiency (CCSVI) …

Association between chronic cerebrospinal venous insufficiency and multiple sclerosis: a systematic review and meta-analysis

J Yang, N Zhang, C Ding, X He, M Li, W Meng… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Numerous studies have indicated that chronic cerebrospinal venous insufficiency
is a potential factor in causing multiple sclerosis in recent years, but this conclusion remains …

[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a failed concept

N Kugler, PJ Patel, CJ Lee - Vascular Specialist International, 2015 - ncbi.nlm.nih.gov
Abstract In 2009 Paolo Zamboni et al. implicated that chronic cerebral venous congestion
lead to the development of multiple sclerosis. In this review, we examined the role of chronic …

Extracranial venous angioplasty is ineffective to treat MS

R Zivadinov, B Weinstock-Guttman - Nature Reviews Neurology, 2018 - nature.com
A randomized, double-blind, sham-controlled trial, Brave Dreams, has shown no clinical or
radiological benefit of percutaneous transluminal angioplasty (PTA) to correct chronic …