(1) Background: Huntington's disease (HD) is rare incurable hereditary neurodegenerative
disorder caused by CAG repeat expansion in the gene coding for the protein huntingtin …

Huntington's disease (HD) is a rare hereditary autosomal dominant neurodegenerative
disorder, which is caused by expression of mutant huntingtin protein (mHTT) with an …

The expansion of a CAG trinucleotide repeat in the huntingtin gene, which produces
huntingtin protein with an expanded polyglutamine tract, is the cause of Huntington's …

Huntington's disease (HD) is an incurable inherited brain disorder characterised by massive
degeneration of striatal neurons, which correlates with abnormal accumulation of misfolded …

Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by
expansion of a translated CAG repeat in the N terminus of the huntingtin (htt) protein. Here …

Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disease
caused by a CAG repeat expansion in exon1 of the huntingtin gene (HTT). This expansion …

Proteolytic fragments of huntingtin (htt) in human lymphoblast cell lines from HD and control
cases were compared to those in human HD striatal and cortical brain regions, by western …

A number of mouse models expressing mutant huntingtin (htt) with an expanded
polyglutamine (polyQ) domain are useful for studying the pathogenesis of Huntington's …

Background The polyglutamine expansion in huntingtin (Htt) protein is a cause of
Huntington's disease (HD). Htt is an essential gene as deletion of the mouse Htt gene …

The mechanism of intercellular transmission of pathological agents in neurodegenerative
diseases has received much recent attention. Huntington's disease (HD) is caused by a …