Nucleosomes compact and organize genetic material on a structural level. However, they
also alter local chromatin accessibility through changes in their position, through the …

Chromatin is a highly dynamic nucleoprotein structure, which orchestrates all nuclear
process from DNA replication to DNA repair, from transcription to recombination. The proper …

Chromatin, a complex of DNA and associated proteins, governs diverse processes including
gene transcription, DNA replication and DNA repair. The fundamental unit of chromatin is …

The functional organization of eukaryotic DNA into chromatin uses histones as components
of its building block, the nucleosome. Histone chaperones, which are proteins that escort …

In eukaryotes, DNA is organized into chromatin, a dynamic structure that enables DNA to be
accessed for processes such as transcription, replication and repair. To form, maintain or …

Histones are highly positively charged proteins that wrap our genome. Their surface
properties also make them prone to nonspecific interactions and aggregation. A class of …

Histone proteins wrap DNA to form nucleosome particles that compact eukaryotic genomes
while still allowing access for cellular processes such as transcription, replication and DNA …

Nucleosomes represent the fundamental repeating unit of eukaryotic DNA, and comprise
eight core histones around which DNA is wrapped in nearly two superhelical turns. Histones …

The mechanism by which newly synthesized histones are imported into the nucleus and
deposited onto replicating chromatin alongside segregating nucleosomal counterparts is …

Our genetic information is tightly packaged into a rather ingenious nucleoprotein complex
called chromatin in a manner that enables it to be rapidly accessed during genomic …