[HTML][HTML] Determining cost and placement decisions for moderate complexity NAATs for tuberculosis drug susceptibility testing

A Malhotra, R Thompson, M De Vos, A David… - Plos one, 2023 - journals.plos.org
Background Access to drug resistant testing for tuberculosis (TB) remains a challenge in
high burden countries. Recently, the World Health Organization approved the use of several …

[图书][B] Improving tuberculosis diagnosis in vulnerable populations: impact and cost-effectiveness of novel, rapid molecular assays

H Sohn - 2016 - search.proquest.com
Tuberculosis (TB) remains a major global public health concern with more than 9.6 million
TB cases and 1.2 million deaths reported in 2014. The reduction of time delays in diagnosis …

[HTML][HTML] Laboratory costs of diagnosing TB in a high multidrug-resistant TB setting

L Cates, V Crudu, A Codreanu, N Ciobanu… - … of Tuberculosis and …, 2021 - ncbi.nlm.nih.gov
Dear Editor, Diagnosing drug resistance to TB requires substantial resources, yet there are
few unit cost estimates for these services. 1–3 We examined the laboratory costs of …

Budget impact of next-generation sequencing for diagnosis of TB drug resistance in Moldova

L Cates, A Codreanu, N Ciobanu… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND Diagnosing drug resistance is critical for choosing effective TB treatment
regimens. Next-generation sequencing (NGS) represents an alternative approach to …

Rapid diagnosis of multidrug-resistant tuberculosis impacts expenditures prior to appropriate treatment: A performance and diagnostic cost analysis

X Li, Y Deng, J Wang, H Jing, W Shu, J Qin… - Infection and Drug …, 2019 - Taylor & Francis
Background In this study, we aimed to describe the impact of the Genotype® MTBDRplus
line probe assay (LPA) for multidrug-resistant tuberculosis (MDR-TB) on total costs in a high …

[HTML][HTML] Cost and affordability analysis of TB-LAMP and Xpert MTB/RIF assays as routine diagnostic tests in peripheral laboratories in Malawi and Vietnam

H Sohn, L Puri, NAT Nguyen, AH Van't Hoog… - Journal of Global …, 2019 - e-jghs.org
Background While the incidence of tuberculosis (TB) is declining globally, the rate of decline
is far too slow to meet the 2035 end TB targets. Use of rapid molecular diagnostics that can …

[HTML][HTML] Targeted genome sequencing for tuberculosis drug susceptibility testing in South Africa: a proposed diagnostic pipeline

TJ Bagratee, DJ Studholme - Access Microbiology, 2024 - microbiologyresearch.org
In July 2023, the World Health Organization (WHO) began recommending targeted next-
generation sequencing (tNGS), due to its ability to detect resistance to many drugs with a …

[HTML][HTML] Rapid, point-of-care diagnosis of tuberculosis with novel Truenat assay: cost-effectiveness analysis for India's public sector

DJ Lee, N Kumarasamy, SC Resch… - PLoS …, 2019 - journals.plos.org
Background Truenat is a novel molecular assay that rapidly detects tuberculosis (TB) and
rifampicin-resistance. Due to the portability of its battery-powered testing platform, it may be …

[HTML][HTML] A systematic review of reported cost for smear and culture tests during multidrug-resistant tuberculosis treatment

C Lu, Q Liu, A Sarma, C Fitzpatrick, D Falzon… - PloS one, 2013 - journals.plos.org
Background In 2011, World Health Organization revised its recommendation for
microbiological monitoring during treatment for multidrug-resistant tuberculosis (MDR-TB) by …

[HTML][HTML] Impact of molecular diagnostics for tuberculosis on patient-important outcomes: a systematic review of study methodologies

SG Schumacher, H Sohn, ZZ Qin, G Gore, JL Davis… - PLoS …, 2016 - journals.plos.org
Background Several reviews on the accuracy of Tuberculosis (TB) Nucleic Acid
Amplification Tests (NAATs) have been performed but the evidence on their impact on …