We present a fast scanning fluorescence optical tomography system for imaging the kinetics
of probe distributions through out the whole body of small animals. Configured in a plane …

Fluorescence imaging is increasingly used to probe protein function and gene expression in
live animals. This technology could enhance the study of pathogenesis, drug development …

We interrogate the ability of free-space fluorescence tomography to image small animals in
vivo using charge-coupled device (CCD) camera measurements over 360-deg noncontact …

Recent advances in optical imaging systems and systemically administered fluorescent
probes have significantly improved the ways by which we can visualize proteomics in vivo. A …

Microscopy of fluorescent proteins has enabled unprecedented insights into visualizing
gene expression in living systems. Imaging deeper into animals, however, has been limited …

Volumetric detection and accurate quantification of fluorescent proteins in entire animals
would greatly enhance our ability to monitor biological processes in vivo. Here we present a …

Fluorescence microscopic imaging is widely used in biomedical research to study molecular
and cellular processes in cell culture or tissue samples. This is motivated by the high …

Methods that allow robust imaging of specific molecular targets and biological processes in
vivo should have widespread applications in biology and clinical medicine. Here we use a …

Fluorescence molecular tomography is an emerging imaging technique that resolves the bio-
distribution of engineered fluorescent probes developed for in vivo reporting of specific …

In vivo imaging of molecular events in small animals has great potential to impact basic
science and drug development. For this reason, several imaging technologies have been …