Osteoarthritis (OA) is an age-related joint disorder and one of the leading causes of physical
disability. In this study, we designed and synthesized a new polysaccharide complex …

Osteoarthritis (OA) is the most prevalent musculoskeletal disorder and the leading cause of
joint disability in elderly patients. In this study, we fabricated strontium chondroitin sulfate …

Magnesium chondroitin sulfate (MgCS) has been fabricated and characterized in this study.
We investigated its morphology, composition as well as structure. The results verify that the …

The preventive and therapeutic effects of chitosan oligosaccharides (COS) on osteoarthritis
(OA) have been rarely investigated. In this study, the protective effects of COS against IL-1β …

Chondroitin sulfate (CS)-calcium complex (CSCa) was fabricated, and the structural
characteristics of CSCa and its proliferative bioactivity to the chondrocyte were investigated …

Knee osteoarthritis (KOA) refers to a common disease in orthopaedics, whereas effective
treatments have been rarely developed. As indicated from existing studies, chondrocyte …

Large bone defects have been a major healthcare concern. These defects are difficult to
heal because of the chronic inflammatory environment surrounding the injury area …

Osteoarthritis (OA) is a degenerative joint disease which is highly prevalent worldwide.
However, no therapy for blocking OA pathogenesis is available currently. In this study …

Bone formation and repair represent a clinical challenge. In this work, we designed and
synthesized strontium Astragalus polysaccharide (APS-Sr), a novel polysaccharide …

Background/Aims: 3, 4, 5-trihydroxy-N-{4-[(5-methylisoxazol-3-yl) sulfamoyl] phenyl}
benzamide (JEZTC), synthesized from gallic acid (GA) and sulfamethoxazole (SMZ), was …