Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

E Yang, X Wang, Z Gong, M Yu, H Wu… - Signal transduction and …, 2020 - nature.com
Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …

Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment

S Tan, Y Yang, W Yang, Y Han, L Huang… - Journal of Experimental …, 2023 - Springer
Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …

Exosome-mediated signaling in epithelial to mesenchymal transition and tumor progression

A Conigliaro, C Cicchini - Journal of clinical medicine, 2018 - mdpi.com
Growing evidence points to exosomes as key mediators of cell–cell communication, by
transferring their specific cargo (eg, proteins, lipids, DNA and RNA molecules) from …

Exosomes in the tumor microenvironment: From biology to clinical applications

VR da Costa, RP Araldi, H Vigerelli, F D'Ámelio… - Cells, 2021 - mdpi.com
Cancer is one of the most important health problems and the second leading cause of death
worldwide. Despite the advances in oncology, cancer heterogeneity remains challenging to …

Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Exosomes regulate the epithelial–mesenchymal transition in cancer

J Jiang, J Li, X Zhou, X Zhao, B Huang, Y Qin - Frontiers in Oncology, 2022 - frontiersin.org
Exosomes are important mediators of intercellular communication and participate in
complex biological processes by transferring a variety of bioactive molecules between cells …

Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer

QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …

Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle

X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …

The role of extracellular vesicles in metabolic reprogramming of the tumor microenvironment

ES Fridman, L Ginini, Z Gil - Cells, 2022 - mdpi.com
The tumor microenvironment (TME) includes a network of cancerous and non-cancerous
cells, together with associated blood vessels, the extracellular matrix, and signaling …

Exosomes and cancer: from molecular mechanisms to clinical applications

A Jafari, A Babajani, M Abdollahpour-Alitappeh… - Medical Oncology, 2021 - Springer
Exosomes are extracellular nanovesicles secreted from almost all types of normal and
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …