Mitochondrial dynamics and metabolic regulation

T Wai, T Langer - Trends in Endocrinology & Metabolism, 2016 - cell.com
Mitochondrial morphology varies tremendously across cell types and tissues, changing
rapidly in response to external insults and metabolic cues, such as nutrient status. The many …

The good and the bad of mitochondrial breakups

HG Sprenger, T Langer - Trends in cell biology, 2019 - cell.com
Mitochondrial morphology is a crucial determinant of mitochondrial and cellular function.
Opposing fusion and fission events shape the tubular mitochondrial reticulum and ensure …

Mitochondrial division and fusion in metabolism

M Roy, PH Reddy, M Iijima, H Sesaki - Current opinion in cell biology, 2015 - Elsevier
Mitochondria govern many metabolic processes. In addition, mitochondria sense the status
of metabolism and change their functions to regulate energy production, cell death, and …

Mitochondrial morphology—emerging role in bioenergetics

CA Galloway, H Lee, Y Yoon - Free Radical Biology and Medicine, 2012 - Elsevier
Dynamic change in mitochondrial shape is a cellular process mediated mainly by fission
and fusion of mitochondria. Studies have shown that mitochondrial fission and fusion are …

[HTML][HTML] Regulation of mammalian mitochondrial dynamics: opportunities and challenges

R Yu, U Lendahl, M Nistér, J Zhao - Frontiers in endocrinology, 2020 - frontiersin.org
Mitochondria are highly dynamic organelles and important for a variety of cellular functions.
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …

Mitochondrial morphology transitions and functions: implications for retrograde signaling?

M Picard, OS Shirihai, BJ Gentil… - American Journal of …, 2013 - journals.physiology.org
In response to cellular and environmental stresses, mitochondria undergo morphology
transitions regulated by dynamic processes of membrane fusion and fission. These events of …

Mitochondrial dynamics and their potential as a therapeutic target

BN Whitley, EA Engelhart, S Hoppins - Mitochondrion, 2019 - Elsevier
Mitochondrial dynamics shape the mitochondrial network and contribute to mitochondrial
function and quality control. Mitochondrial fusion and division are integrated into diverse …

Mitochondrial morphology in metabolic diseases

CA Galloway, Y Yoon - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: Mitochondria are the cellular energy-producing organelles and are at the
crossroad of determining cell life and death. As such, the function of mitochondria has been …

[HTML][HTML] Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure

M Liesa, OS Shirihai - Cell metabolism, 2013 - cell.com
Mitochondrial fusion, fission, and mitophagy form an essential axis of mitochondrial quality
control. However, quality control might not be the only task carried out by mitochondrial …

Mitochondrial movers and shapers: recent insights into regulators of fission, fusion and transport

NU Fatima, V Ananthanarayanan - Current Opinion in Cell Biology, 2023 - Elsevier
Mitochondria are highly dynamic organelles that undergo rapid morphological adaptations
influencing their number, transport, cellular distribution, and function, which in turn facilitate …