A new set of 1, 2, 3-triazoles was designed and synthesized to evaluate their potential to
inhibit the growth of cancer cells. Thiazole, thiazolone, and hydrazine as effective fragments …

A series of novel compounds carrying 1, 2, 4-triazole scaffold was synthesized and
evaluated for their anticancer activity against a panel of cancer cell lines using MTT assay …

Abstract Three novel series of 1, 2, 4‐triazole derivatives were designed and synthesized as
potential adenosine A2B receptor antagonists. The design of the new compounds depended …

Abstract A series of novel 4, 5‐diphenyloxazol‐1, 2, 4‐triazole derivatives (6 a–6 l) were
synthesized and screened for anticancer activity against the prostate lung cancer cell lines …

A series of 1, 2, 4 triazole derivatives (H7-12) have been synthesized by reacting an excess
of hydrazine hydrate with carbothioamide derivatives (H1-6). The final compounds (HB1 …

In the present study, two important starting materials and 18 new 1, 2, 4-triazole compounds
with mono ring system have been synthesized and characterized. The mono system showed …

Cancer is still one of the leading causes of death worldwide. Many researchers are working
to design and develop heterocyclic‐based drugs with the potential to treat cancer at various …

Background: In recent years, there has been a crucial need for the design and development
of novel anticancer drugs that can lessen the serious health problems and unwanted side …

Herein, we reported the synthesis of nineteen novel 1, 2, 4-triazole derivatives including 1, 3-
diphenyl-2-(1H-1, 2, 4-triazol-1-yl) propan-1-ones (7a-e), 1-(1, 3-diphenylpropan-2-yl)-1 H-1 …

Cellular tumor antigen p53 is significant for cancer prevention and its mutation is most
documented genomic change in human cancers. Thus, restoration of p53 function by …