Survivin is a dual regulator of cell proliferation and cell viability overexpressed in most
human tumors. Although strategies to lower survivin levels have been pursued for rational …

BACKGROUND Survivin counteracts cell death and controls mitotic progression. The
objectives of the current study were to compare the expression patterns of survivin in normal …

Survivin is a prosurvival protein overexpressed in many cancers through mechanisms that
remain poorly explored, and is implicated in control of tumor progression and resistance to …

Survivin, a prominent anticancer target, is ubiquitously expressed in a plethora of cancers
and the evolving complexity in functional regulation of survivin is yet to be deciphered …

Survivin is the smallest member of the inhibitor of apoptosis protein family, which has key
roles in regulating cell division and inhibiting apoptosis by blocking caspase activation …

OBJECTIVES: To assess the effect of survivin gene expression on the proliferation of
prostate cancer (PCa) cells and study the association of suvivin and its spliced isoforms …

Despite its genetic complexity and multifactoriality, two processes appear almost universally
compromised in cancer: the control of cell proliferation and the regulation of cell lifespan …

Survivin is a novel member of the inhibitor of apoptosis (IAP) protein family, and its aberrant
expression in cancer cells has been shown to be associated with tumorigenesis, cancer …

Survivin, a member of the inhibitor of apoptosis family, is upregulated in multiple cancers
including ovarian cancer, but is rarely detectable in normal tissues. We previously reported …

Survivin, a member of the inhibitor of apoptosis protein family, has been associated with
protection from cell apoptosis and regulation of mitosis. Survivin exhibits low to undetectable …