Simultaneous stabilization and functionalization of gold nanoparticles via biomolecule conjugation: Progress and perspectives

JW Lee, SR Choi, JH Heo - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Gold nanoparticles (AuNPs) are used in various biological applications because of their
small surface area-to-volume ratios, ease of synthesis and modification, low toxicity, and …

Design and applications of gold nanoparticle conjugates by exploiting biomolecule–gold nanoparticle interactions

S Su, X Zuo, D Pan, H Pei, L Wang, C Fan, W Huang - Nanoscale, 2013 - pubs.rsc.org
Gold nanoparticles (AuNPs) are a type of widely used nanomaterials with unique chemical
and physical properties. AuNPs can be readily synthesized, and modified with various …

Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules

L Vigderman, ER Zubarev - Advanced drug delivery reviews, 2013 - Elsevier
This review will first look at the various covalent strategies that have been developed to
attach drugs to gold nanoparticles as well as the strengths and limitations of such strategies …

Functionalized gold nanoparticles for the binding, stabilization, and delivery of therapeutic DNA, RNA, and other biological macromolecules

RK DeLong, CM Reynolds, Y Malcolm… - Nanotechnology …, 2010 - Taylor & Francis
Nanotechnology has virtually exploded in the last few years with seemingly limitless
opportunity across all segments of our society. If gene and RNA therapy are to ever realize …

Polyvalent DNA nanoparticle conjugates stabilize nucleic acids

DS Seferos, AE Prigodich, DA Giljohann, PC Patel… - Nano …, 2009 - ACS Publications
Polyvalent oligonucleotide gold nanoparticle conjugates have unique fundamental
properties including distance-dependent plasmon coupling, enhanced binding affinity, and …

Thermal stability of DNA functionalized gold nanoparticles

F Li, H Zhang, B Dever, XF Li, XC Le - Bioconjugate chemistry, 2013 - ACS Publications
Therapeutic uses of DNA functionalized gold nanoparticles (DNA-AuNPs) have shown great
potential and exciting opportunities for disease diagnostics and treatment. Maintaining …

Colloidal stability of gold nanoparticles modified with thiol compounds: bioconjugation and application in cancer cell imaging

J Gao, X Huang, H Liu, F Zan, J Ren - Langmuir, 2012 - ACS Publications
Gold nanoparticles (GNPs) are attractive alternative optical probes and good biocompatible
materials due to their special physical and chemical properties. However, GNPs have a …

Rapid synthesis of DNA-functionalized gold nanoparticles in salt solution using mononucleotide-mediated conjugation

W Zhao, L Lin, IM Hsing - Bioconjugate chemistry, 2009 - ACS Publications
DNA functionalized gold-nanoparticles (Au-nps) have been broadly used as labeling
reagents in the development of molecular diagnostics as well as building blocks in …

Role of gold nanoparticles in advanced biomedical applications

SA Bansal, V Kumar, J Karimi, AP Singh… - Nanoscale …, 2020 - pubs.rsc.org
Gold nanoparticles (GNPs) have generated keen interest among researchers in recent years
due to their excellent physicochemical properties. In general, GNPs are biocompatible …

Ultrastable and biofunctionalizable gold nanoparticles

A Gupta, DF Moyano, A Parnsubsakul… - … applied materials & …, 2016 - ACS Publications
Gold nanoparticles provide an excellent platform for biological and material applications due
to their unique physical and chemical properties. However, decreased colloidal stability and …