Rationale A high risk of post‐operative recurrence contributes to the poor prognosis and low
survival rate of oesophageal squamous cell carcinoma (ESCC) patients. Increasing …

During tumorigenesis and metastasis, integrins regulate localization and activity of
proteolytic enzymes that remodel the extracellular matrix. Previous studies have …

Abstract Background Mesothelial E-and P-selectins substantially mediate the intraperitoneal
spread of Pancreatic ductal adenocarcinoma (PDA) cells in xenograft models. In the …

Integrin subunit alpha V (ITGAV), a member of integrin family of extracellular matrix
receptors, is involved in many types of cancer. In this study, the expression levels, clinical …

Valid biomarkers for a better prognostic prediction of the clinical course in esophageal
adenocarcinoma (EAC) are still not implemented. Integrin alpha V (ITGAV), a …

Background Osteosarcoma (OS) is the most common primary malignant bone tumor. Hence,
there is an urgent need to identify effective and safe therapeutic agents against OS. It has …

Background Little is known about the relationship between integrin subunit alpha V (ITGAV)
and cancers, including small cell lung cancer (SCLC). Methods Using large sample size …

The objective of this study was to investigate the role of αv-integrin subunit (ITGAV, CD51) in
invasion and metastasis of the laryngeal and hypopharyngeal squamous cell carcinomas …

Background Integrin alpha 2 (ITGA2) is highly expressed in various cancers. ITGA2 up
regulation promotes tumor proliferation, invasion, migration, and angiogenesis and ITGA2 is …

Background Pancreatic cancer is one of the most aggressive malignancies without effective
targeted therapies. MUC1 has emerged as a potential common target for cancer therapy …