Improved antioxidant activity of rutin via lipase‐mediated esterification with oleic acid

Y Liu, Q Wang, C Liu, H Yang, L Jia… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND Oxidation is a major problem for oils and fats, which can be mitigated by
antioxidants. Rutin has excellent antioxidant activity, but its poor lipid solubility greatly limits …

Lipophilic rutin derivatives for antioxidant protection of oil-based foods

J Viskupicova, M Danihelova, M Ondrejovic, T Liptaj… - Food Chemistry, 2010 - Elsevier
The lipase-catalysed synthesis of lipophilic flavonoid antioxidants via rutin acylation with
fatty acids (C4–C18) in 2-methylbutan-2-ol was investigated. Conversion yields of rutin fatty …

Antioxidant efficacies of rutin and rutin esters in bulk oil and oil‐in‐water emulsion

BM Lue, ADM Sørensen, C Jacobsen… - European Journal of …, 2017 - Wiley Online Library
The use of flavonoids as antioxidants in food formulations is limited due to their solubility
and thereby their localization in the food products. However, enzymatic alkylation of …

Enhanced antioxidant capacity of lipoic acid in different food systems through lipase‐mediated esterification with phytosterols

WS He, Y Sun, Z Li, H Yang, J Li… - Journal of the …, 2022 - Wiley Online Library
BACKGROUND α‐Lipoic acid has excellent antioxidant activity, but its poor lipid solubility
greatly limits its practical application. This study was undertaken (i) to develop a novel and …

Lipase mediated synthesis of rutin fatty ester: Study of its process parameters and solvent polarity

C Vaisali, PD Belur, I Regupathi - Food chemistry, 2017 - Elsevier
Lipophilization of antioxidants is recognized as an effective strategy to enhance solubility
and thus effectiveness in lipid based food. In this study, an effort was made to optimize rutin …

Antioxidant properties of modified rutin esters by DPPH, reducing power, iron chelation and human low density lipoprotein assays

BM Lue, NS Nielsen, C Jacobsen, L Hellgren, Z Guo… - Food Chemistry, 2010 - Elsevier
Practical limitations exist regarding the effectiveness of flavonoids as antioxidants in many
food systems, possibly due to their poor solubility and miscibility in lipidic environments …

Enzymatic synthesis of lipophilic rutin and vanillyl esters from fish byproducts

B Mbatia, SS Kaki, B Mattiasson, F Mulaa… - Journal of Agricultural …, 2011 - ACS Publications
Lipase-catalyzed synthesis of lipophilic phenolic antioxidants was carried out with a
concentrate of n-3 polyunsaturated fatty acids (PUFAs), recovered from oil extracted from …

Enzymatic acylation of rutin with benzoic acid ester and lipophilic, antiradical, and antiproliferative properties of the acylated derivatives

HM Li, TT Xu, QX Peng, YS Chen, H Zhou… - Journal of Food …, 2021 - Wiley Online Library
Abstract Rutin (3′, 4′, 5, 7‐tetrahydroxy‐flavone‐3‐rutinoside) was enzymatically acylated
with benzoic acid and its esters (methyl benzoate and vinyl benzoate) using Thermomyces …

Lipophilized rosmarinic acid: Impact of alkyl type and food matrix on antioxidant activity, and optimized enzymatic production

M Mardani, K Badakné, I Szedljak, C Sörös, J Farmani - Food Chemistry, 2024 - Elsevier
In this study, the initial focus was on exploring the simultaneous impact of the oil-based food
matrix and the polarity of rosmarinic acid derivatives on the antioxidant properties …

[PDF][PDF] from synthesis to biological health effects and application

JVVT Maliar - Journal of Food and Nutrition Research (ISSN 1336 …, 2017 - vup.sk
Flavonoids are promising compounds with a significant therapeutic potential. However, rutin
efficiency after oral administration is limited due to its poor bioavailability. This paper …