Novel imidazolium-thiohydantoin hybrids and their Mn (III) complexes for antimicrobial and anti-liver cancer applications

LA Ismail, R Zakaria, EM Hassan, MY Alfaifi, AA Shati… - RSC …, 2022 - pubs.rsc.org
We present the effective synthesis and structural characterization of three novel imidazolium-
thiohydantoin ligands (IMTHs, 5a–c) and their Mn (III) complexes (Mn (III) IMTHs, 6a–c) in …

New Mn (III)/Fe (III) complexes with thiohydantoin-supported imidazolium ionic liquids for breast cancer therapy

OAA Ali, W Abd El-Fattah, MY Alfaifi, AA Shati… - Inorganica Chimica …, 2023 - Elsevier
This study offers, for the first time, the design and synthesis of hybrids integrating
imidazolium ionic liquids (IMILs) and thiohydantoins (THs) motifs and their Mn/Fe (III) …

Development of new azomethine metal chelates derived from isatin: DFT and Pharmaceutical Studies

AA Al-Shamry, MM Khalaf, HMA El-Lateef, TA Yousef… - Materials, 2022 - mdpi.com
Through the condensation of isatin (indoline-2, 3-dione) and aniline in a 1: 1 ratio, a Schiff
base ligand was synthesized and characterized via (1H-NMR, mass, IR, UV-Vis) spectra …

Structural characterization and biological evaluation of antimony (III) and bismuth (III) complexes with imidazolidine-2-thione

O Ucar, AM Grześkiewicz, C Banti… - Journal of Molecular …, 2021 - Elsevier
There is an emerging interest in the synthesis of antimony (III) and bismuth (III) complexes
with sulfur containing ligands, this has been attributed to their wide structural diversity and …

Synthesis, magnetic moment, antibacterial, and antifungal studies of INH incorporating Schiff base metal complexes

ZT Omar, S Jadhav, S Shejul, P Chavan… - Polycyclic Aromatic …, 2023 - Taylor & Francis
The Isoniazid (INH) ring system is one of the most important heterocycles in nature, as it
represents an important structural motif of many biological compounds. It possesses …

Novel Mn (II) and Cu (II) metal complexes with sulfa drug-derived ligands as potent antimicrobial and anticancer agents: In vitro studies, ADMET profile and molecular …

MA Bourouai, A Bouchoucha, KS Larbi, S Cosnier… - Polyhedron, 2024 - Elsevier
The present work deals with the synthesis, characterization, and pharmaceutical potential
evaluation of new biologically active Mn (II) and Cu (II) complexes with Schiff bases derived …

Synthesis, crystal structure, spectral and DFT studies of potent isatin derived metal complexes

SH Sumrra, AH Atif, MN Zafar, M Khalid… - Journal of Molecular …, 2018 - Elsevier
The isatin-core in compounds offers exciting perspectives in medicinal and pharmacological
research. The present study reports the successful development of new isatin-core transition …

Coordination behavior, structural, statistical and theoretical investigation of biologically active metal-based isatin compounds

SH Sumrra, F Mushtaq, F Ahmad, R Hussain, W Zafar… - Chemical Papers, 2022 - Springer
Isatin-core-containing ligands were synthesized by reacting an equimolar ratio of isatin with
ethanolamine and anthranilic acid, respectively. The ligands were characterized by using FT …

Synthesis, molecular structure determination, and biological studies on E-1-p-ethoxyphenyl-4-hydroximinomethyl imidazole metal complexes

R Lopez-Garzon, JM Lopez-Gonzalez… - Journal of inorganic …, 1990 - Elsevier
Metal complexes of E-1-p-ethoxyphenyl-4-hydroximinomethyl imidazole (EALDH) were
prepared and characterized by infrared, electronic, 1 H and 13 C NMR two-dimensional …

Design anticancer potential of Zn (II) isoleucinedithiocarbamate complex on MCF-7 cell lines: synthesis, characterization, molecular docking, molecular dynamic …

R Irfandi, I Raya, A Ahmad, A Fudholi, Riswandi… - Molecular Diversity, 2023 - Springer
Cisplatin is a cancer medication widely used today, but it still poses some problems due to
its toxic properties in the body. To overcome this issue, a new complex has been developed …