Mozambique is one of the four African countries which account for over half of all malaria
deaths worldwide, yet little is known about the parasite genetic structure in that country. We …

The emergence of Plasmodium falciparum drug resistance threatens the efficacy of
antimalarial therapies globally. Population genomic studies have been instrumental in …

Background Drug resistance is one of the greatest challenges of malaria control programme
in Mali. Recent advances in next-generation sequencing (NGS) technologies provide new …

Background: Antimalarial drug resistance is a major obstacle to sustainable malaria control.
Here we use amplicon sequencing to describe molecular markers of drug resistance in …

Sulfadoxine-pyrimethamine (SP) resistance impairs the efficacy of antimalarial drugs.
Monitoring molecular markers in exported malaria infections provides an efficient way to …

Plasmodium falciparum malaria cases in Africa represent over 90% of the global burden
with Mali being amongst the 11 highest burden countries that account for 70% of this annual …

Introduction Genomic data constitute a valuable adjunct to routine surveillance that can
guide programmatic decisions to reduce the burden of infectious diseases. However …

Genetic polymorphisms in P. falciparum can be used to indicate the parasite's susceptibility
to antimalarial drugs as well as its geographical origin. Both of these factors are key to …

A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

Background Current malaria control and elimination strategies rely mainly on efficacious
antimalarial drugs. However, drug resistance is a major threat facing malaria control …