[HTML][HTML] Small-molecule theranostics in Alzheimer's disease

Á Sarabia-Vallejo, P López-Alvarado… - European Journal of …, 2023 - Elsevier
Alzheimer's Disease (AD) remains one of the most challenging health-related issues for our
society, that is becoming increasingly prevalent, especially in developed countries, due to …

From companion diagnostics to theranostics: a new avenue for alzheimer's disease? Miniperspective

ML Bolognesi, A Gandini, F Prati… - Journal of Medicinal …, 2016 - ACS Publications
The recent literature signals a growing paradigm shift toward integrating therapeutics and
diagnostics rather than developing and deploying them separately. In this gradual move …

Novel therapeutic strategies for dementia

R Cacabelos, C Torrellas, I Carrera… - CNS & Neurological …, 2016 - ingentaconnect.com
Dementia represents a major problem of health and disability, with a relevant economic
impact on our society. Despite important advances in pathogenesis, diagnosis and …

[HTML][HTML] Alzheimer's disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs

AR Monteiro, DJ Barbosa, F Remião, R Silva - Biochemical Pharmacology, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases that
affect millions of people worldwide, with both prevalence and incidence increasing with age …

Recent developments in natural and synthetic drug research for Alzheimer's disease

G Orhan, I Orhan, B Sener - Letters in Drug Design & Discovery, 2006 - ingentaconnect.com
Alzheimer's Disease (AD) is a progressive and degenerative neurological disorder
characterized by loss of cognition and memory. However, the pathogenesis of AD is still not …

Alzheimer's disease: emerging trends in small molecule therapies

T Mohamed, P PN Rao - Current medicinal chemistry, 2011 - ingentaconnect.com
Alzheimer's disease (AD) is a highly complex and rapidly progressive neurodegenerative
disorder characterized by the systemic collapse of cognitive function and formation of dense …

Progress in target drug molecules for Alzheimer's disease

J Xie, R Liang, Y Wang, J Huang… - Current Topics in …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease that 4 widespread in the
elderly. The etiology of AD is complicated, and its pathogenesis is still unclear. Although …

Current and emerging therapies for Alzheimer's disease

HB Nygaard - Clinical therapeutics, 2013 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …

[HTML][HTML] Impact of new drugs for therapeutic intervention in Alzheimer's disease

J Olloquequi, M Ettcheto, A Cano… - Frontiers in Bioscience …, 2022 - imrpress.com
The increases in population ageing and growth are leading to a boosting in the number of
people living with dementia, Alzheimer's disease (AD) being the most common cause. In …

Current and emerging pharmacological targets for the treatment of Alzheimer's disease

A Morsy, PC Trippier - Journal of Alzheimer's Disease, 2019 - content.iospress.com
No cure or disease-modifying therapy for Alzheimer's disease (AD) has yet been realized.
However, a multitude of pharmacological targets have been identified for possible …