Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort
AT Hastie, FJ Martinez, JL Curtis… - The Lancet …, 2017 - thelancet.com
Background Increased concentrations of eosinophils in blood and sputum in chronic
obstructive pulmonary disease (COPD) have been associated with increased frequency of …
obstructive pulmonary disease (COPD) have been associated with increased frequency of …
Eosinophils in COPD: just another biomarker?
Eosinophils are innate immune cells that, under certain conditions, can be recruited to the
lungs, where they have an incompletely understood role in health and disease. Eosinophils …
lungs, where they have an incompletely understood role in health and disease. Eosinophils …
Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials
D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis
Background Inhaled corticosteroids are important in the management of chronic obstructive
pulmonary disease (COPD), but can slightly increase the risk of pneumonia in patients with …
pulmonary disease (COPD), but can slightly increase the risk of pneumonia in patients with …
Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort
VL Kim, NA Coombs, KJ Staples… - European …, 2017 - Eur Respiratory Soc
Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) predicts
response to treatment, especially corticosteroids. We studied the nature of eosinophilic …
response to treatment, especially corticosteroids. We studied the nature of eosinophilic …
[HTML][HTML] Blood eosinophil levels as a biomarker in COPD
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder and patients
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …
Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait
B David, M Bafadhel, L Koenderman, A De Soyza - Thorax, 2021 - thorax.bmj.com
The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many
diagnostic, prognostic, treatment and management challenges, as the pathogenesis of …
diagnostic, prognostic, treatment and management challenges, as the pathogenesis of …
The reproducibility of COPD blood eosinophil counts
T Southworth, G Beech, P Foden… - European …, 2018 - Eur Respiratory Soc
Post hoc and pre-specified analyses of chronic obstructive pulmonary disease (COPD)
randomised controlled trials have shown that higher blood eosinophil counts predict greater …
randomised controlled trials have shown that higher blood eosinophil counts predict greater …
[HTML][HTML] Relationship between blood eosinophils and clinical characteristics in a cross-sectional study of a US population-based COPD cohort
RL DiSantostefano, D Hinds, H Van Le, NC Barnes - Respiratory medicine, 2016 - Elsevier
Background Current evidence suggests that blood eosinophil levels (Eos) are associated
with chronic obstructive pulmonary disease (COPD) treatment response and natural history …
with chronic obstructive pulmonary disease (COPD) treatment response and natural history …
Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD
NA Negewo, VM McDonald, KJ Baines… - … journal of chronic …, 2016 - Taylor & Francis
Introduction Sputum eosinophilia occurs in approximately one-third of stable chronic
obstructive pulmonary disease (COPD) patients and can predict exacerbation risk and …
obstructive pulmonary disease (COPD) patients and can predict exacerbation risk and …
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