Prevalence of Mycoplasma genitalium Infection, Antimicrobial Resistance Mutations, and Symptom Resolution Following Treatment of Urethritis

LH Bachmann, RD Kirkcaldy, WM Geisler… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Antimicrobial resistance in Mycoplasma genitalium (MG), a cause of
urethritis, is a growing concern. Yet little is known about the geographic distribution of MG …

Mycoplasma genitalium in Symptomatic Male Urethritis: Macrolide Use Is Associated With Increased Resistance

Y Li, X Su, W Le, S Li, Z Yang… - Clinical Infectious …, 2020 - academic.oup.com
Background Mycoplasma genitalium (MG) causes symptomatic urethritis in men, and can
infect alone or together with other sexually transmitted infection (STI) agents. Methods The …

Mycoplasma genitalium in the US (MyGeniUS): Surveillance Data From Sexual Health Clinics in 4 US Regions

LE Manhart, G Leipertz, OO Soge… - Clinical Infectious …, 2023 - academic.oup.com
Background Mycoplasma genitalium (MG) is on the CDC Watch List of Antimicrobial
Resistance Threats, yet there is no systematic surveillance to monitor change. Methods We …

Transmission and Selection of Macrolide Resistant Mycoplasma genitalium Infections Detected by Rapid High Resolution Melt Analysis

J Twin, JS Jensen, CS Bradshaw, SM Garland… - PloS one, 2012 - journals.plos.org
Background Mycoplasma genitalium (MG) causes urethritis, cervicitis and pelvic
inflammatory disease. The MG treatment failure rate using 1 g azithromycin at an Australian …

High Prevalence of Antibiotic-Resistant Mycoplasma genitalium in Nongonococcal Urethritis: The Need for Routine Testing and the Inadequacy of Current Treatment …

MJ Pond, AV Nori, AA Witney… - Clinical infectious …, 2014 - academic.oup.com
Background. Empirical antibiotic therapy for nongonococcal urethritis (NGU) and cervicitis is
aimed at Chlamydia trachomatis, but Mycoplasma genitalium, which also commonly causes …

Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance

TRH Read, CK Fairley, SN Tabrizi… - Clinical Infectious …, 2017 - academic.oup.com
Background. We evaluated the impact of extended azithromycin (1.5 g over 5 days) on
selection of macrolide resistance and microbiological cure in men with Mycoplasma …

Combination Therapy for Mycoplasma genitalium, and New Insights Into the Utility of parC Mutant Detection to Improve Cure

LA Vodstrcil, EL Plummer, M Doyle… - Clinical Infectious …, 2022 - academic.oup.com
Background Mycoplasma genitalium (MG) infection is challenging to cure because of rising
antimicrobial resistance and limited treatment options. Methods This was a prospective …

Outcomes of Resistance-guided Sequential Treatment of Mycoplasma genitalium Infections: A Prospective Evaluation

TRH Read, CK Fairley, GL Murray… - Clinical Infectious …, 2019 - academic.oup.com
Background Rising macrolide and quinolone resistance in Mycoplasma genitalium
necessitate new treatment approaches. We evaluated outcomes of sequential antimicrobial …

Remarkable increase in fluoroquinolone-resistant Mycoplasma genitalium in Japan

M Kikuchi, S Ito, M Yasuda, T Tsuchiya… - Journal of …, 2014 - academic.oup.com
Objectives We determined the prevalence of macrolide and fluoroquinolone resistance-
associated mutations in Mycoplasma genitalium DNA specimens from men with non …

Men who have sex with men with mycoplasma genitalium–positive Nongonococcal urethritis are more likely to have macrolide-resistant strains than men with only …

R McIver, D Jalocon, A McNulty… - Sexually transmitted …, 2019 - journals.lww.com
Background Mycoplasma genitalium was previously less common among men who have
sex with men (MSM) compared with men with only female partners (MSW) in men with …