Vasopressin as possible treatment option in autism spectrum disorder

K László, D Vörös, P Correia, CL Fazekas, B Török… - Biomedicines, 2023 - mdpi.com
Autism spectrum disorder (ASD) is rather common, presenting with prevalent early problems
in social communication and accompanied by repetitive behavior. As vasopressin was …

Vasopressin deficiency: a hypothesized driver of both social impairment and fluid imbalance in autism spectrum disorder

L Clarke, N Gesundheit, EH Sherr, AY Hardan… - Molecular …, 2024 - nature.com
Scientific naming conventions are often idiosyncratic. For example, biological processes
have acquired names after a physician who described a syndrome (Alois Alzheimer), the …

Vasopressin in the amelioration of social functioning in autism spectrum disorder

MA Hendaus, FA Jomha, AH Alhammadi - Journal of Clinical Medicine, 2019 - mdpi.com
Autism spectrum disorder (ASD) is a developmental disability described by diagnostic
criteria that comprise deficits in social communication and the existence of repetitive …

Tinkering with the vasopressin pathway in autism

B Forgeot d'Arc, L Mottron, M Elsabbagh… - Science Translational …, 2019 - science.org
Tinkering with the vasopressin pathway in autism | Science Translational Medicine news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …

The promiscuity of the oxytocin–vasopressin systems and their involvement in autism spectrum disorder

AM Borie, C Theofanopoulou, E Andari - Handbook of clinical neurology, 2021 - Elsevier
Oxytocin and vasopressin systems have been studied separately in autism spectrum
disorder (ASD). Here, we provide evidence from an evolutionary and neuroscience …

Differences in oxytocin and vasopressin levels in individuals suffering from the autism spectrum disorders vs general population–a systematic review

KM Wilczyński, I Zasada, A Siwiec… - … disease and treatment, 2019 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder
characterized by deficits in social interactions, communication, and the presence of …

A single dose, randomized, controlled proof-of-mechanism study of a novel vasopressin 1a receptor antagonist (RG7713) in high-functioning adults with autism …

D Umbricht, M del Valle Rubido, E Hollander… - …, 2017 - nature.com
The core symptoms of autism spectrum disorder (ASD) include impaired social
communication, repetitive behaviors, and restricted interests. No effective pharmacotherapy …

ASD and Genetic Associations with Receptors for Oxytocin and Vasopressin—AVPR1A, AVPR1B, and OXTR

SM Francis, SJ Kim, E Kistner-Griffin, S Guter… - Frontiers in …, 2016 - frontiersin.org
Background: There are limited treatments available for autism spectrum disorder (ASD).
Studies have reported significant associations between the receptor genes of oxytocin (OT) …

A review of oxytocin and arginine-vasopressin receptors and their modulation of autism spectrum disorder

I Cataldo, A Azhari, G Esposito - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Oxytocin (OXT) and arginine-vasopressin (AVP) play a key regulatory part in social and
affiliative behaviors; two aspects highly compromised in Autism Spectrum Disorder (ASD) …

A phase 2 clinical trial of a vasopressin V1a receptor antagonist shows improved adaptive behaviors in men with autism spectrum disorder

F Bolognani, M del Valle Rubido… - Science translational …, 2019 - science.org
There are no approved pharmacological therapies to address the core symptoms of autism
spectrum disorder (ASD), namely, persistent deficits in social communication and social …