Back and to the future: from neurotoxin‐induced to human Parkinson's disease models
Parkinson's disease (PD) is an age‐related neurodegenerative disorder characterized by
motor symptoms such as tremor, slowness of movement, rigidity, and postural instability, as …
motor symptoms such as tremor, slowness of movement, rigidity, and postural instability, as …
Neurotoxin-induced rodent models of Parkinson's disease: benefits and drawbacks
Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by cardinal motor impairments, including akinesia and tremor, as well as by a …
characterized by cardinal motor impairments, including akinesia and tremor, as well as by a …
Parkinson's disease: genetic versus toxin‐induced rodent models
M Terzioglu, D Galter - The FEBS journal, 2008 - Wiley Online Library
Parkinson's disease (PD), a common progressive neurodegenerative disorder, is
characterized by degeneration of dopamine neurons in the substantia nigra and neuronal …
characterized by degeneration of dopamine neurons in the substantia nigra and neuronal …
[HTML][HTML] Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions
A Dovonou, C Bolduc, V Soto Linan, C Gora… - Translational …, 2023 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
A survey from 2012 of evidence for the role of neuroinflammation in neurotoxin animal models of Parkinson's disease and potential molecular targets
CP Ramsey, MG Tansey - Experimental neurology, 2014 - Elsevier
Parkinson's disease (PD) is a neurodegenerative movement disorder that results from the
progressive loss of dopaminergic neurons in the midbrain substantia nigra pars compacta …
progressive loss of dopaminergic neurons in the midbrain substantia nigra pars compacta …
Parkinson's disease: a rethink of rodent models
HL Melrose, SJ Lincoln, GM Tyndall… - Experimental Brain …, 2006 - Springer
Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from
genetic risk factors, environmental exposures and most likely a combination of both. Rodent …
genetic risk factors, environmental exposures and most likely a combination of both. Rodent …
Experimental animal models of Parkinson's disease: a transition from assessing symptomatology to α-synuclein targeted disease modification
WKD Ko, E Bezard - Experimental neurology, 2017 - Elsevier
With the understanding that α-synuclein plays a major role in the pathogenesis of
Parkinson's disease (PD), novel animal models have been developed for conducting …
Parkinson's disease (PD), novel animal models have been developed for conducting …
Animal models of Parkinson's disease: a guide to selecting the optimal model for your research
Parkinson's disease (PD) is a complex, multisystem disorder characterised by α-synuclein
(SNCA) pathology, degeneration of nigrostriatal dopaminergic neurons, multifactorial …
(SNCA) pathology, degeneration of nigrostriatal dopaminergic neurons, multifactorial …
Disease model: Parkinson's disease
S Shimohama, H Sawada, Y Kitamura… - Trends in molecular …, 2003 - cell.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder that is primarily
characterized by the degeneration of dopaminergic neurons in the nigrostriatal pathway …
characterized by the degeneration of dopaminergic neurons in the nigrostriatal pathway …
Animal models of Parkinson's disease progression
GE Meredith, PK Sonsalla, MF Chesselet - Acta neuropathologica, 2008 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder whose etiology is not
understood. This disease occurs both sporadically and through inheritance of single genes …
understood. This disease occurs both sporadically and through inheritance of single genes …