This study evaluated the in vitro and in vivo performance of antibiotic-releasing porous
polymethylmethacrylate (PMMA)-based space maintainers comprising a gelatin hydrogel …

Antibiotic-releasing porous poly (methyl methacrylate)(PMMA) space maintainers,
comprising PMMA with an aqueous porogen and a poly (DL-lactic-co-glycolic acid)(PLGA) …

The use of a strategy involving space maintenance as the initial step of a two-stage
regenerative medicine approach toward reconstructing significant bony or composite tissue …

An antibiotic-releasing porous polymethylmethacrylate (PMMA) construct was developed to
maintain the bony space and prime the wound site in the initial step of a two-stage …

Severe injuries in the craniofacial complex, resulting from trauma or pathology, present
several challenges to functional and aesthetic reconstruction. The anatomy and position of …

Abstract Space maintainers (SMs) used for craniofacial reconstruction function to preserve
the void space created upon bone loss and promote soft tissue healing over the defect …

Current treatment of traumatic craniofacial injuries often involves early free tissue transfer,
even if the recipient site is contaminated or lacks soft tissue coverage. There are no current …

Infections represent a significant source of site morbidity following tissue trauma. Scarring
and tissue adhesion remain the challenging issues yet to be solved. Prolonged inflammation …

Advanced scaffolds used in tissue regenerating applications should be designed to address
clinically relevant complications such as surgical site infection associated with surgical …

Biodegradable carriers containing gentamicin for local treatment of bone infection were
developed. This paper describes the preparation and in vitro evaluation of these …