Investigating the psychopharmacology of cognitive affective bias in rats using an affective tone discrimination task
MH Anderson, MR Munafò, ESJ Robinson - Psychopharmacology, 2013 - Springer
Rationale Affective states are known to influence behaviour in humans resulting in cognitive
affective biases, which may play an important role in the development and treatment of …
affective biases, which may play an important role in the development and treatment of …
Affective biases in humans and animals
ESJ Robinson, JP Roiser - Translational neuropsychopharmacology, 2016 - Springer
Depression is one of the most common but poorly understood psychiatric conditions.
Although drug treatments and psychological therapies are effective in some patients, many …
Although drug treatments and psychological therapies are effective in some patients, many …
[HTML][HTML] A translational rodent assay of affective biases in depression and antidepressant therapy
SA Stuart, P Butler, MR Munafo, DJ Nutt… - …, 2013 - nature.com
The subjective measures used to study mood disorders in humans cannot be replicated in
animals; however, the increasing application of objective neuropsychological methods …
animals; however, the increasing application of objective neuropsychological methods …
[HTML][HTML] Further validation of the affective bias test for predicting antidepressant and pro-depressant risk: effects of pharmacological and social manipulations in male …
Rationale Affective biases are hypothesised to contribute to the cause and treatment of
mood disorders. We have previously found that affective biases, associated with learning …
mood disorders. We have previously found that affective biases, associated with learning …
Using the affective bias test to predict drug‐induced negative affect: implications for drug safety
SA Stuart, CM Wood… - British journal of …, 2017 - Wiley Online Library
Background and Purpose Predicting the risk of drug‐induced adverse psychiatric effects is
important but currently not possible in non‐human species. We investigated whether the …
important but currently not possible in non‐human species. We investigated whether the …
[HTML][HTML] Evaluation of a novel translational task for assessing emotional biases in different species
MH Anderson, C Hardcastle, MR Munafò… - Cognitive, Affective, & …, 2012 - Springer
Abstract Changes in the processing of emotional information are key features of affective
disorders. Neuropsychological tests based on emotional faces or words are used to detect …
disorders. Neuropsychological tests based on emotional faces or words are used to detect …
A repeated measures cognitive affective bias test in rats: comparison with forced swim test
B Aliphon, T Dai, J Moretti, M Penrose-Menz… - …, 2023 - Springer
Rationale There is an urgent need to identify behaviours in animals that can provide insight
into the aetiology and potential treatment of depression in humans. Objectives This study …
into the aetiology and potential treatment of depression in humans. Objectives This study …
A novel task to assess mood congruent memory bias in non-human animals
OHP Burman, MT Mendl - Journal of Neuroscience Methods, 2018 - Elsevier
Background Assessing the affective state of animals is important for a range of research
areas, including neuroscience. The use of cognitive judgement and attention biases to …
areas, including neuroscience. The use of cognitive judgement and attention biases to …
[HTML][HTML] A shortened protocol for assessing cognitive bias in rats
NM Brydges, L Hall - Journal of Neuroscience Methods, 2017 - Elsevier
Background Reliable measurement of affective state in animals is a significant goal of
animal welfare. Such measurements would also improve the validity of pre-clinical mental …
animal welfare. Such measurements would also improve the validity of pre-clinical mental …
Modelling cognitive affective biases in major depressive disorder using rodents
CA Hales, SA Stuart, MH Anderson… - British journal of …, 2014 - Wiley Online Library
Major depressive disorder (MDD) affects more than 10% of the population, although our
understanding of the underlying aetiology of the disease and how antidepressant drugs act …
understanding of the underlying aetiology of the disease and how antidepressant drugs act …