Mapping quantitative trait loci in complex pedigrees: a two-step variance component approach

AW George, PM Visscher, CS Haley - Genetics, 2000 - academic.oup.com
There is a growing need for the development of statistical techniques capable of mapping
quantitative trait loci (QTL) in general outbred animal populations. Presently used variance …

Mapping quantitative trait loci in outbred pedigrees

I Hoeschele - Handbook of Statistical Genetics, 2004 - Wiley Online Library
In this chapter, we present statistical methods for mapping quantitative trait loci (QTLs) in
outbred or complex pedigrees. Such pedigrees exist primarily in livestock populations, also …

[图书][B] Quantitative trait loci analysis in animals

JI Weller - 2009 - books.google.com
Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock
production. This book covers various statistical methods that have been used or proposed …

[PDF][PDF] Advances in quantitative trait locus mapping

C Haley - From Jay Lush to Genomics: Visions for animal …, 1999 - Citeseer
The mapping of loci underlying variation in quantitative traits is proving to be a powerful tool
in genetic studies of animals and other organisms. Quantitative trait locus (QTL) mapping in …

[PDF][PDF] Mapping quantitative trait loci in outcross populations via residual maximum likelihood. I. Methodology

FE Grignola, I Hoeschele, B Tier - Genetics selection evolution, 1996 - gse-journal.org
A residual maximum likelihood method, implemented with a derivative-free algorithm, was
derived for estimating position and variance contribution of a single QTL together with …

[HTML][HTML] Statistical properties of QTL linkage mapping in biparental genetic populations

H Li, S Hearne, M Bänziger, Z Li, J Wang - Heredity, 2010 - nature.com
Quantitative trait gene or locus (QTL) mapping is routinely used in genetic analysis of
complex traits. Especially in practical breeding programs, questions remain such as how …

A mixture model approach to the mapping of quantitative trait loci in complex populations with an application to multiple cattle families

RC Jansen, DL Johnson, JAM Van Arendonk - Genetics, 1998 - academic.oup.com
A mixture model approach is presented for the mapping of one or more quantitative trait loci
(QTLs) in complex populations. In order to exploit the full power of complete linkage maps …

Advances in statistical methods to map quantitative trait loci in outbred populations

I Hoeschele, P Uimari, FE Grignola, Q Zhang… - Genetics, 1997 - academic.oup.com
Statistical methods to map quantitative trait loci (QTL) in outbred populations are reviewed,
extensions and applications to human and plant genetic data are indicated, and areas for …

Multiple-trait mapping of quantitative trait loci after selective genotyping using logistic regression

JM Henshall, ME Goddard - Genetics, 1999 - academic.oup.com
Experiments to map QTL usually measure several traits, and not uncommonly genotype only
those animals that are extreme for some trait (s). Analysis of selectively genotyped, multiple …

QTL analysis: unreliability and bias in estimation procedures

V Hyne, MJ Kearsey, DJ Pike, JW Snape - Molecular Breeding, 1995 - Springer
Several statistical methods which employ multiple marker data are currently available for the
analysis of quantitative trait loci (QTL) in experimental populations. Although comparable …