[HTML][HTML] Large Animal Models in Cardiovascular Research

H Osada, K Murata, H Masumoto - Animal Models and …, 2022 - intechopen.com
Studies of not only preclinical cardiovascular research but also those of life science,
medical, and pharmacological fields commonly utilize small animal models. However, for the …

The representative porcine model for human cardiovascular disease

Y Suzuki, AC Yeung, F Ikeno - BioMed Research International, 2011 - Wiley Online Library
To improve human health, scientific discoveries must be translated into practical
applications. Inherent in the development of these technologies is the role of preclinical …

The pig as an optimal animal model for cardiovascular research

H Jia, Y Chang, J Song - Lab Animal, 2024 - nature.com
Cardiovascular disease is a worldwide health problem and a leading cause of morbidity and
mortality. Preclinical cardiovascular research using animals is needed to explore potential …

Large mammalian animal models of heart disease

P Camacho, H Fan, Z Liu, JQ He - Journal of cardiovascular development …, 2016 - mdpi.com
Due to the biological complexity of the cardiovascular system, the animal model is an urgent
pre-clinical need to advance our knowledge of cardiovascular disease and to explore new …

Use of larger species such as dog and pig as model systems to study cardiac disease

BA Coppola, JH Omens - Drug Discovery Today: Disease Models, 2008 - Elsevier
The advent of genetically engineered mouse models has greatly expanded the scientific
tools available to study cellular and molecular mechanisms of cardiac disease. But in many …

Animal models for cardiovascular research

YT Shen, L Chen, JM Testani, CP Regan… - Animal Models for the …, 2017 - Elsevier
With advances in molecular and genomic research offering novel insights into
cardiovascular diseases, recently many transgenic animal models have been developed …

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on …

J van der Velden, FW Asselbergs… - Cardiovascular …, 2022 - academic.oup.com
Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …

[图书][B] Animal Models for the Study of Human Disease: Chapter 7. Animal Models of Myocardial Disease

RA Breckenridge - 2013 - books.google.com
Myocardial disease is one of the largest medical burdens facing populations of the
developed world. Increasing diabetes and obesity in both the developed and developing …

[图书][B] Animal models in cardiovascular research

D Gross - 2009 - books.google.com
This new edition of Animal Models in Cardiovascular Research describes historical and
recent advances in our understanding of the cardiovascular system from studies conducted …

Transgenic rabbit models for studying human cardiovascular diseases

X Peng - Comparative medicine, 2012 - ingentaconnect.com
Cardiovascular diseases involve the heart or blood vessels and remain a leading cause of
morbidity and mortality in developed countries. A variety of animal models have been used …