Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance

J Gault, H Sarin, NA Awadallah, R Shenkar… - Neurosurgery, 2004 - journals.lww.com
Abstract CEREBROVASCULAR MALFORMATIONS AFFECT more than 3% of the
population, exposing them to a lifetime risk of hemorrhagic stroke, seizures, and focal …

Cerebral cavernous malformations: from genes to proteins to disease

DD Cavalcanti, MYS Kalani, NL Martirosyan… - Journal of …, 2012 - thejns.org
Over the past half century molecular biology has led to great advances in our understanding
of angio-and vasculogenesis and in the treatment of malformations resulting from these …

Epidemiology, genetics, pathophysiology, and prognostic classifications of cerebral arteriovenous malformations

A Ozpinar, G Mendez, AA Abla - Handbook of Clinical Neurology, 2017 - Elsevier
Arteriovenous malformations (AVMs) are vascular deformities involving fistula formation of
arterial to venous structures without an intervening capillary bed. Such anomalies can prove …

Cerebral arteriovenous malformations. Part 2: physiology

P Moftakhar, JS Hauptman, D Malkasian… - Neurosurgical focus, 2009 - thejns.org
Object The scientific understanding of the nature of arteriovenous malformations (AVMs) in
the brain is evolving. It is clear from current work that AVMs can undergo a variety of …

Cerebral cavernous malformation: from mechanism to therapy

DA Snellings, CC Hong, AA Ren… - Circulation …, 2021 - Am Heart Assoc
Cerebral cavernous malformations are acquired vascular anomalies that constitute a
common cause of central nervous system hemorrhage and stroke. The past 2 decades have …

Vis-à-vis: a focus on genetic features of cerebral cavernous malformations and brain arteriovenous malformations pathogenesis

C Scimone, L Donato, S Marino, C Alafaci… - Neurological …, 2019 - Springer
Cerebrovascular malformations include a wide range of blood vessel disorders affecting
brain vasculature. Neuroimaging differential diagnosis can result unspecific due to similar …

Molecular and cellular biology of cerebral arteriovenous malformations: a review of current concepts and future trends in treatment

L Rangel-Castilla, JJ Russin, E Martinez-del-Campo… - Neurosurgical …, 2014 - thejns.org
Object Arteriovenous malformations (AVMs) are classically described as congenital static
lesions. However, in addition to rupturing, AVMs can undergo growth, remodeling, and …

Biology of vascular malformations of the brain

GG Leblanc, E Golanov, IA Awad, WL Young… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—This review discusses recent research on the genetic,
molecular, cellular, and developmental mechanisms underlying the etiology of vascular …

Diagnosis and treatment of arteriovenous malformations

JP Mohr, J Kejda-Scharler, J Pile-Spellman - Current neurology and …, 2013 - Springer
Brain arteriovenous malformations (bAVMs) are among the least common of causes of brain
hemorrhage, seizures, or headaches. Embedded in the brain, their widely varying size …

Cerebral arteriovenous malformations. Part 1: cellular and molecular biology

P Moftakhar, JS Hauptman, D Malkasian… - Neurosurgical focus, 2009 - thejns.org
Object The scientific understanding of the nature of arteriovenous malformations (AVMs) in
the brain is evolving. It is clear from current work that AVMs can undergo a variety of …