Adult neurogenesis mainly occurs at the subventricular zone (SVZ) on the walls of the lateral
ventricle and the subgranular zone (SGZ) of the dentate gyrus (DG). However, the majority of …

Ischemic stroke is one of the most intractable diseases of the central nervous system and is
also a major cause of mortality and disability in adult humans. Unfortunately, current …

In the aftermath of an acute stroke, numerous signaling cascades that reshape the brain
both in the perilesional zone as well as in more distal regions are activated. Despite …

Adult neurogenesis in the subventricular zone is a topic of intense research, since it has vast
implications for the fundamental understanding of the neurobiology of the brain and its …

Stroke affects one in every six people worldwide, and is the leading cause of adult disability.
After stroke, some limited spontaneous recovery occurs, the mechanisms of which remain …

A bulk of experimental evidence supports the idea that the stroke-damaged adult brain
makes an attempt to repair itself by producing new neurons also in areas where …

Ischemic stroke is a very common cerebrovascular accident that occurred in adults and
causes higher risk of neural deficits. After ischemic stroke, patients are often left with severe …

Introduction Despite attempts to prevent brain injury during the hyperacute phase of stroke,
most sufferers end up with significant neuronal loss and functional deficits. The use of cell …

Stroke activates neural stem cells in the ventricular-subventricular zone (V/SVZ) of the lateral
ventricle, which increases neuroblasts and oligodendrocyte progenitor cells (OPCs). Within …

Ischaemic stroke is among the most common yet most intractable types of central nervous
system (CNS) injury in the adult human population. In the acute stages of disease, neurons …