Wall teichoic acid substitution with glucose governs phage susceptibility of Staphylococcus epidermidis

C Beck, J Krusche, A Notaro, A Walter, L Kränkel… - Mbio, 2024 - Am Soc Microbiol
The species-and clone-specific susceptibility of Staphylococcus cells for bacteriophages is
governed by the structures and glycosylation patterns of wall teichoic acid (WTA) …

Temperate Phages of Staphylococcus aureus

H Ingmer, D Gerlach, C Wolz - Microbiology spectrum, 2019 - Am Soc Microbiol
Most Staphylococcus aureus isolates carry multiple bacteriophages in their genome, which
provide the pathogen with traits important for niche adaptation. Such temperate S. aureus …

An accessory wall teichoic acid glycosyltransferase protects Staphylococcus aureus from the lytic activity of Podoviridae

X Li, D Gerlach, X Du, J Larsen, M Stegger, P Kühner… - Scientific reports, 2015 - nature.com
Many Staphylococcus aureus have lost a major genetic barrier against phage infection,
termed clustered regularly interspaced palindromic repeats (CRISPR/cas). Hence, S. aureus …

Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM

G Xia, L Maier, P Sanchez-Carballo, M Li, M Otto… - Journal of Biological …, 2010 - ASBMB
Wall teichoic acid (WTA) glycopolymers are major constituents of cell envelopes in
Staphylococcus aureus and related Gram-positive bacteria with important roles in cell wall …

Staphylococcus epidermidis phages transduce antimicrobial resistance plasmids and mobilize chromosomal islands

L Fišarová, T Botka, X Du, I Mašlaňová, P Bárdy… - Msphere, 2021 - Am Soc Microbiol
Staphylococcus epidermidis is a leading opportunistic pathogen causing nosocomial
infections that is notable for its ability to form a biofilm and for its high rates of antibiotic …

Determinants of Phage Host Range in Staphylococcus Species

AG Moller, JA Lindsay, TD Read - Applied and environmental …, 2019 - Am Soc Microbiol
Bacteria in the genus Staphylococcus are important targets for phage therapy due to their
prevalence as pathogens and increasing antibiotic resistance. Here we review …

The phages of staphylococci: critical catalysts in health and disease

A Hatoum-Aslan - Trends in microbiology, 2021 - cell.com
The phages that infect Staphylococcus species are dominant residents of the skin
microbiome that play critical roles in health and disease. While temperate phages, which …

Biosynthesis of the unique wall teichoic acid of Staphylococcus aureus lineage ST395

V Winstel, P Sanchez-Carballo, O Holst, G Xia… - MBio, 2014 - Am Soc Microbiol
The major clonal lineages of the human pathogen Staphylococcus aureus produce cell wall-
anchored anionic poly-ribitol-phosphate (RboP) wall teichoic acids (WTA) substituted with d …

[HTML][HTML] Phage susceptibility determinants of the opportunistic pathogen Staphylococcus epidermidis

C Beck, J Krusche, AMA Elsherbini, X Du… - Current Opinion in …, 2024 - Elsevier
Highlights•Temperate phages of Staphylococcus epidermidis facilitate horizontal gene
transfer.•Wall teichoic acid glycosylation determines binding of S. epidermidis phages.•The …

Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle

X Du, J Larsen, M Li, A Walter, C Slavetinsky… - Nature …, 2021 - nature.com
Most clonal lineages of Staphylococcus epidermidis are commensals present on human
skin and in the nose. However, some globally spreading healthcare-associated and …