[HTML][HTML] Mesenchymal stem cell-derived exosomes in ophthalmology: a comprehensive review

KY Wu, H Ahmad, G Lin, M Carbonneau, SD Tran - Pharmaceutics, 2023 - mdpi.com
Over the past decade, the field of mesenchymal stem cell (MSC) therapy has exhibited rapid
growth. Due to their regenerative, reparatory, and immunomodulatory capacities, MSCs …

Therapeutic potential of mesenchymal stem cell-derived exosomes in the treatment of eye diseases

CR Harrell, B Simovic Markovic, C Fellabaum… - Cell Biology and …, 2018 - Springer
Mesenchymal stem cells (MSCs) were, due to their immunomodulatory and pro-angiogenic
characteristics, extensively explored as new therapeutic agents in cell-based therapy of …

[HTML][HTML] Therapeutic potential of microvesicles in cell therapy and regenerative medicine of ocular diseases with an especial focus on mesenchymal stem cells …

LM Rad, AV Yumashev, BM Hussen, HH Jamad… - Frontiers in …, 2022 - frontiersin.org
These days, mesenchymal stem cells (MSCs), because of immunomodulatory and pro-
angiogenic abilities, are known as inevitable factors in regenerative medicine and cell …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles as a new therapeutic strategy for ocular diseases

B Yu, XR Li, XM Zhang - World journal of stem cells, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have attracted considerable attention for their activity in the
treatment of refractory visual disorders. Since MSCs were found to possess the beneficial …

Pathological role of inflammation in ocular disease progress and its targeting by mesenchymal stem cells (MSCs) and their exosome; current status and prospect

A Nouralishahi, N Fazlinejad, RDC Pecho… - … -Research and Practice, 2023 - Elsevier
Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …

Advances in exosome therapies in ophthalmology–From bench to clinical trial

A Sanghani, P Andriesei, KN Kafetzis… - Acta …, 2022 - Wiley Online Library
During the last decade, the fields of advanced and personalized therapeutics have been
constantly evolving, utilizing novel techniques such as gene editing and RNA therapeutic …

Effect of mesenchymal stem cell‐derived exosomes on retinal injury: A review of current findings

R Nuzzi, P Caselgrandi, A Vercelli - Stem cells international, 2020 - Wiley Online Library
In recent years, various studies have followed in the literature on the therapeutic effects of
mesenchymal stem cells (MSC) on damage in retinal cells. The evidence that MSCs exert …

[HTML][HTML] Mesenchymal stem cells and exosomes: A novel therapeutic approach for corneal diseases

B Bhujel, SH Oh, CM Kim, YJ Yoon, YJ Kim… - International Journal of …, 2023 - mdpi.com
The cornea, with its delicate structure, is vulnerable to damage from physical, chemical, and
genetic factors. Corneal transplantation, including penetrating and lamellar keratoplasties …

Advances in development of exosomes for ophthalmic therapeutics

Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

Extracellular vesicles as reconfigurable therapeutics for eye diseases: Promises and hurdles

F Shekari, M Abyadeh, A Meyfour, M Mirzaei… - Progress in …, 2023 - Elsevier
A large number of people worldwide suffer from visual impairment. However, most available
therapies rely on impeding the development of a particular eye disorder. Therefore, there is …