Lipid bilayers play an important role in the pathological assembly of amyloidogenic proteins
and peptides. This assembly yields oligomers and fibrils, which are highly toxic protein …

Amyloid formation is a hallmark of many medical diseases including diabetes type 2,
Alzheimer's and Parkinson diseases. Under these pathological conditions, misfolded …

Abrupt aggregation of misfolded proteins is a hallmark of the large group of amyloid
pathologies that include diabetes type 2, Alzheimer and Parkinson's diseases. Protein …

Abrupt aggregation of misfolded proteins is a hallmark of many medical pathologies
including diabetes type 2, Alzheimer and Parkinson diseases. This results in the formation of …

Biophysical properties of plasma membranes are determined by a chemical structure of
phospholipids, including saturation of fatty acids and charge of polar heads of these …

Amyloid oligomers and fibrils are protein aggregates that cause an onset and progression of
many neurodegenerative diseases, diabetes type 2 and systemic amyloidosis. Although a …

Formation of protein amyloid fibrils consists of a series of intermediates including oligomeric
aggregates, proto-fibrillar structures, and finally mature fibrils. Recent studies show higher …

Phosphatidic acid (PA) is a unique plasma membrane lipid that contains fatty acids (FAs)
with different lengths and degrees of unsaturation. Under physiological conditions, PA acts …

Abrupt aggregation of misfolded proteins is a hallmark of a large number of severe
pathologies, including diabetes types 1 and 2, Alzheimer, and Parkinson diseases. A …

The misfolding, amyloid aggregation, and fibril formation of intrinsically disordered
proteins/peptides (or amyloid proteins) have been shown to cause a number of disorders …