ABSTRACT A new animal model for the purpose of studying superficial infections is
presented. In this model an infection is established by disruption of the skin barrier by partial …

Staphylococcus aureus has remained an important cause of nosocomial wound infections,
but standardized or reproducible systems for analyzing cutaneous infections caused by S …

Reproducible experimental surgical-wound infections in mice for use in the evaluation of
topical antibacterial agents are described. The experimental would was created on the …

Bacterial skin and soft tissue infections are abundant worldwide and many are caused by
Staphylococcus aureus. Indeed, S. aureus is the leading cause of skin and soft tissue …

Meticillin-resistant Staphylococcus aureus (MRSA) is a rapidly spreading pathogen
associated predominantly with skin infections. The lack of clinical evidence indicating the …

Staphylococcus aureus cells were inoculated on the cut wounds in the skin of
cyclophosphamide-treated mice. Biopsy specimens were taken from three mice at 1, 3, 6 …

Experimental mouse models of bacterial skin infections that have been described show that
pathogenic microorganisms can readily invade the epidermis and dermis to produce …

Objectives: Dermal and subdermal bacterial infections, caused mainly by Staphylococcus
aureus, are currently treated by systemic antibiotics. The aim of the present study was to …

Staphylococcus aureus UC® 9271 mixed with dextran or gelatin microcarrier beads and
injected subcutaneously into mice resulted in the formation of reproducible, sustained …

This was a preliminary investigation to define the conditions of colonization of a human skin
equivalent (SE) model with cutaneous microorganisms. SEs of 24 mm diameter were …