Nasal polyposis pathophysiology: Endotype and phenotype open issues

G Brescia, C Zanotti, D Parrino, U Barion… - American Journal of …, 2018 - Elsevier
Purpose Endotyping chronic rhinosinusitis with nasal polyps (CRSwNP) poses a challenge
for rhinologists nowadays. Phenotyping CRSwNP proved inappropriate as an approach to …

[HTML][HTML] Subtyping of polyposis nasi: phenotypes, endotypes and comorbidities

M Koennecke, L Klimek, J Mullol, P Gevaert… - Allergo journal …, 2018 - Springer
Background Chronic rhinosinusitis (CRS) is a heterogeneous, multifactorial inflammatory
disease of the nasal and paranasal mucosa. It has not been possible to date to develop an …

A review of classification schemes for chronic rhinosinusitis with nasal polyposis endotypes

SK Dennis, K Lam, A Luong - Laryngoscope investigative …, 2016 - Wiley Online Library
Objective The recent development of endotypes to categorize disease variants of chronic
rhinosinusitis (CRS) reflects an evolving understanding of the various pathophysiologic and …

[HTML][HTML] Chronic rhinosinusitis with nasal polyps and asthma

TM Laidlaw, J Mullol, KM Woessner, N Amin… - The Journal of Allergy …, 2021 - Elsevier
Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) characterized by a type 2
immune signature often have severe and recurrent disease. Lower airway conditions such …

[HTML][HTML] New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis

I Striz, K Golebski, Z Strizova, S Loukides… - Clinical …, 2023 - portlandpress.com
Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are
chronic respiratory diseases. These two disorders often co-exist based on common …

A classification of chronic rhinosinusitis with nasal polyps based on structured histopathology

G Brescia, L Alessandrini, L Giacomelli… - …, 2020 - Wiley Online Library
Aims In chronic rhinosinusitis with nasal polyps (CRSwNP), tools based on objective
evidence, such as histopathology, are needed to assist clinical decision‐making. The main …

Chronic rhinosinusitis with nasal polyps

WW Stevens, RP Schleimer, RC Kern - The journal of allergy and clinical …, 2016 - Elsevier
Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed
by the presence of both subjective and objective evidence of chronic sinonasal …

Predictive markers of long-term recurrence in chronic rhinosinusitis with nasal polyps

D Rosati, C Rosato, G Pagliuca, B Cerbelli… - American journal of …, 2020 - Elsevier
Background In last years, many attempts were made to recognize chronic rhinosinusitis with
nasal polyps (CRSwNP) phenotypes focusing on identifying relevant key pathogenic …

Computed tomography findings can help identify different chronic rhinosinusitis with nasal polyp phenotypes

LT Roland, S Marcus, JS Schertzer… - American Journal of …, 2020 - journals.sagepub.com
Background Chronic rhinosinusitis with nasal polyps (CRSwNPs) has several phenotypes.
Objectives The goal of this study was to evaluate computed tomography (CT) findings …

[PDF][PDF] Cellular phenotyping of chronic rhinosinusitis with nasal polyps

H Lou, Y Meng, Y Piao, N Zhang, C Bachert, C Wang… - Rhinology, 2016 - academia.edu
Background: Defining the phenotypes of chronic rhinosinusitis with nasal polyps (CRSwNP)
with prognosis may lead to delivery of personalized treatment. This study aimed to identify …