[HTML][HTML] A systematic review and meta-analysis of murine models of uremic cardiomyopathy
Chronic kidney disease (CKD) triggers the risk of developing uremic cardiomyopathy as
characterized by cardiac hypertrophy, fibrosis and functional impairment. Traditionally …
characterized by cardiac hypertrophy, fibrosis and functional impairment. Traditionally …
Cardiomyopathy in chronic kidney disease: clinical features, biomarkers and the contribution of murine models in understanding pathophysiology
CVC Junho, J Frisch, J Soppert… - Clinical Kidney …, 2023 - academic.oup.com
The cardiorenal syndrome (CRS) is described as a multi‐organ disease encompassing
bidirectionally heart and kidney. In CRS type 4, chronic kidney disease (CKD) leads to …
bidirectionally heart and kidney. In CRS type 4, chronic kidney disease (CKD) leads to …
Myocardial dysfunction occurs prior to changes in ventricular geometry in mice with chronic kidney disease (CKD)
PD Winterberg, R Jiang, JT Maxwell… - Physiological …, 2016 - Wiley Online Library
Uremic cardiomyopathy is responsible for high morbidity and mortality rates among patients
with chronic kidney disease (CKD), but the underlying mechanisms contributing to this …
with chronic kidney disease (CKD), but the underlying mechanisms contributing to this …
Mapping cardiac remodeling in chronic kidney disease
Patients with advanced chronic kidney disease (CKD) mostly die from sudden cardiac death
and recurrent heart failure. The mechanisms of cardiac remodeling are largely unclear. To …
and recurrent heart failure. The mechanisms of cardiac remodeling are largely unclear. To …
Is uremic cardiomyopathy a direct consequence of chronic kidney disease?
S Chinnappa, SS Hothi, LB Tan - Expert review of cardiovascular …, 2014 - Taylor & Francis
Heart failure is a major cause of morbidity and mortality in chronic kidney disease (CKD).
Rather than merely secondary to traditional vascular factors, CKD is also an independent …
Rather than merely secondary to traditional vascular factors, CKD is also an independent …
[HTML][HTML] Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease
Aims Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular
events and exhibit myocardial changes including left ventricular (LV) hypertrophy and …
events and exhibit myocardial changes including left ventricular (LV) hypertrophy and …
Cardiac remodeling in chronic kidney disease
Cardiac remodeling occurs frequently in chronic kidney disease patients and affects quality
of life and survival. Current treatment options are highly inadequate. As kidney function …
of life and survival. Current treatment options are highly inadequate. As kidney function …
[HTML][HTML] Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure
AM Siedlecki, X Jin, AJ Muslin - Kidney international, 2009 - Elsevier
Chronic kidney disease is often complicated by uremic cardiomyopathy that consists of left
ventricular hypertrophy and interstitial fibrosis. It is thought that hypertension and volume …
ventricular hypertrophy and interstitial fibrosis. It is thought that hypertension and volume …
Pathological cardiac remodeling occurs early in CKD mice from unilateral urinary obstruction, and is attenuated by Enalapril
O Ham, W Jin, L Lei, HH Huang, K Tsuji, M Huang… - Scientific reports, 2018 - nature.com
Cardiovascular disease constitutes the leading cause of mortality in patients with chronic
kidney disease (CKD) and end-stage renal disease. Despite increasing recognition of a …
kidney disease (CKD) and end-stage renal disease. Despite increasing recognition of a …
Cardiac metabolic remodelling in chronic kidney disease
N Patel, MM Yaqoob, D Aksentijevic - Nature Reviews Nephrology, 2022 - nature.com
Chronic kidney disease (CKD) affects millions of people globally and, for most patients, the
risk of developing cardiovascular disease is higher than that of progression to kidney failure …
risk of developing cardiovascular disease is higher than that of progression to kidney failure …