A review on development of bio-active thiosemicarbazide derivatives: Recent advances

PT Acharya, ZA Bhavsar, DJ Jethava, DB Patel… - Journal of Molecular …, 2021 - Elsevier
There has been substantial attention in the expansion of new thiosemicarbazide derivatives
with diverse biological activities in recent years. Therefore, many scientists have prepared …

Thiazole derivatives in medicinal chemistry: Recent advancements in synthetic strategies, structure activity relationship and pharmacological outcomes

A Singh, D Malhotra, K Singh, R Chadha… - Journal of Molecular …, 2022 - Elsevier
Thiazole derivatives remains honored heterocycles in the field of medicinal chemistry. This
scaffold has been proven as a universal motif that is present in numerous pharmacologically …

Synthesis, characterization, biochemical, and molecular modeling studies of carvacrol‐based new thiosemicarbazide and 1, 3, 4‐thiadiazole derivatives

T Alagöz, FG Çalişkan, HG Bilgiçli… - Archiv der …, 2023 - Wiley Online Library
A series of carvacrol‐based thiosemicarbazide (3a–e) and 1, 3, 4‐thiadiazole‐2‐amine (4a–
e) were designed and synthesized for the first time. The structures were characterized by …

[HTML][HTML] Exploring the synthesis, structure, spectroscopy and biological activities of novel 4-benzylidene-1-(2-(2, 4-dichloro phenyl) acetyl) thiosemicarbazide …

M Waheed, S Idris, F Jan, A Alam, M Ibrahim… - Saudi Pharmaceutical …, 2023 - Elsevier
Background Novel α-amylase inhibitors play a crucial role in managing diabetes and
obesity, contributing to improved public health by addressing these challenging and …

Synthetic and medicinal perspective of thiazolidinones: A review

SK Manjal, R Kaur, R Bhatia, K Kumar, V Singh… - Bioorganic …, 2017 - Elsevier
In the modern scenario, thiazolidinone scaffold has emerged as a very potent scaffold as per
its clinical significance concerned. It has attracted the keen interest of the researchers due to …

Multifaceted bioactivity of thiosemicarbazide derivatives: Synthesis, characterization, and DFT investigations on inhibition of α-amylase, hydroxyl radical scavenging …

S Idris, F Jan, M Waheed, A Alam, M Ibrahim… - Journal of Molecular …, 2024 - Elsevier
In this study, eight bioactive thiosemicarbazide derivatives (3a-h) were synthesized and
characterized through 1 HNMR, 13 CNMR and Mass spectroscopic techniques. Finally, their …

Bioactive thiazine and benzothiazine derivatives: green synthesis methods and their medicinal importance

SL Badshah, A Naeem - Molecules, 2016 - mdpi.com
Thiazines are a group of heterocyclic organic compounds that are still largely unexplored for
their pharmacological activities. There are different available methods for the synthesis of …

Synthesis and antiviral properties of novel indole-based thiosemicarbazides and 4-thiazolidinones

G Cihan-Üstündağ, E Gürsoy, L Naesens… - Bioorganic & Medicinal …, 2016 - Elsevier
A novel series of indolylthiosemicarbazides (6a–6g) and their cyclization products, 4-
thiazolidinones (7a–7g), have been designed, synthesized and evaluated, in vitro, for their …

A retrospect on antimicrobial potential of thiazole scaffold

I Mishra, R Mishra, S Mujwar… - Journal of …, 2020 - Wiley Online Library
Due to its appreciable diversity in biological actions, thiazole and its substituted
components, a significant class of heterocyclic compounds has developed as an influential …

An overview on synthetic 2-aminothiazole-based compounds associated with four biological activities

M Farouk Elsadek, B Mohamed Ahmed… - Molecules, 2021 - mdpi.com
Amongst sulfur-and nitrogen-containing heterocyclic compounds, the 2-aminothiazole
scaffold is one of the characteristic structures in drug development as this essential …